Robot-assisted Partial Nephrectomy with and without Mixed Reality - REALITATEM study #
Duarte DM Junior et al. · International braz j urol · 2026
Urology · Randomized controlled trial · n: 45 patients
“Analyses indicated statistically significant difference in ischemia time favoring RG (p = 0.045), with a mean difference of 3.8 minutes.”
p = 0.045
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Preoperative Immersive Virtual Reality Applied to Percutaneous Nephrolithotomy: A Prospective Randomized Clinical Study of Surgical Planning and Clinical Outcomes #
Cumpanas AD et al. · The Journal of urology · 2025
Urology · Randomized controlled trial · n: 175 patients
“Preoperative visualization of the iVR model resulted in a changed calyx of entry in 30% of cases.”
30%
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Preliminary Study on the Accuracy Comparison Between 3D-Printed Bone Models and Naked-Eye Stereoscopy-Based Virtual Reality Models for Presurgical Molding in Orbital Floor Fracture Repair #
Tsuchiya M et al. · Applied Sciences · 2025
Oral & maxillofacial / craniofacial · Comparative study · n: 11 orbital fractures
“Between modalities, no significant differences were found; HD and RMSE were 2.95 ± 0.94 mm and 1.28 ± 0.49 mm.”
DOI
Clinical Practice and Survey of Three-Dimensional Images, Virtual Reality, Augmented Reality and Mixed Reality for Robotic-Assisted Surgery in Urology-"Anatomy on the Border" Expert Consensus Meeting #
Kobayashi S et al. · Asian journal of endoscopic surgery · 2025
Urology · Survey/user study
“Thirty-two urologists surveyed reported using 3D imaging for preoperative evaluation (84%) and to understand anatomy (75%), with 97% reporting clinical benefits and 85% indicating that it improved the quality of surgery.”
97%
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Patient-specific virtual and mixed reality for immersive, experiential anatomy education and for surgical planning in temporal bone surgery #
Yamazaki A et al. · Auris, nasus, larynx · 2021
ENT / head & neck · Survey/user study · n: 1 patient
“Most participants were favorable about the VR model and considered HMD as superior to a flat computer screen. 91% of the participants agreed or somewhat agreed that VR through HMD is cost effective.”
91%
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Advancements in 3D modeling technologies for congenital heart disease: integrating 3D printing, virtual reality, and holograms #
Bertelli F et al. · Pediatric radiology · 2026
Congenital heart · Narrative review
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Merging Robotics and Virtual Reality for Brain Tumor Surgery: A New Frontier in Surgical Innovation #
Karimi A et al. · World neurosurgery · 2026
Neurosurgery · Narrative review
“However, challenges like high costs, lack of haptic feedback, and steep learning curves limit widespread use.”
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Extended reality for perforator visualization in deep inferior epigastric perforator autologous breast reconstruction: A systematic review #
Zijlstra K et al. · JPRAS open · 2026
Plastic & reconstructive · Systematic review
“XR use decreased operative time, with AR reducing intraoperative perforator localization time from 20 min using handheld Doppler US to 2.3 min.”
2.3 min
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Virtual Reality in Neurosurgery: Advancing Training, Education, and Surgical Planning #
Saher L et al. · Asian journal of neurosurgery · 2026
Neurosurgery · Narrative review
“High cost, lack of numerous skilled operators, user discomfort, and no proper ethical protocols are critical hindrances that need to be addressed.”
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Virtual reality in percutaneous coronary intervention: from coronary imaging and procedural planning to patient care #
Skalidis I et al. · The international journal of cardiovascular imaging · 2026
Adult cardiac & structural heart · Narrative review
“The principal barriers are the absence of robust haptic feedback, cost, limited validation, cybersickness, and a scarcity of outcome-driven randomised trials.”
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Advancing Surgical Practice With Mixed Reality: Current Innovations and Future Prospects #
Ke Y, Hu K · MedComm – Future Medicine · 2025
Multi-specialty · Narrative review
“However, current limitations include insufficient computational and display capabilities of head‐mounted displays, inadequate accuracy in spatial registration, high costs, workflow complexity, and unresolved ethical concerns.”
DOI
The use of three-dimensional printing and virtual reality technologies in orthopaedics-with a focus on orthopaedic trauma #
Policicchio TJ et al. · Journal of clinical orthopaedics and trauma · 2025
Orthopedics · Narrative review
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Advancing Spine Surgery: Innovations for Spatial Computing Integration #
Elsayed GA et al. · World neurosurgery · 2025
Spine · Narrative review
“However, challenges remain, particularly with respect to clinical validation, cost-effectiveness, and ethical considerations.”
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3-dimensional reconstruction and mixed reality in thoracic surgery: a narrative review and user guide #
Pohlman A et al. · Journal of thoracic disease · 2025
Thoracic · Narrative review
“Currently, the primary limitations are varying accuracy of models, available evidence for use, uptake by surgeons, and cost of the technology.”
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The use of virtual reality and augmented reality in oral and maxillofacial surgery: A narrative review #
Stucki J et al. · Oral surgery, oral medicine, oral pathology and oral radiology · 2024
Oral & maxillofacial / craniofacial · Narrative review
“Virtual reality/AR technology offers significant potential in various aspects, including student education, resident evaluation, surgical planning, and overall surgical implementation.”
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Use of Virtual Reality and 3D Models in Contemporary Practice of Cardiology #
Minga I et al. · Current cardiology reports · 2024
Adult cardiac & structural heart · Narrative review
“The incorporation of 3D reconstruction modeling has significantly enhanced our understanding of patient anatomy and morphology, thereby improving diagnostic accuracy and patient outcomes.”
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Mixed reality in interventional radiology: a focus on first clinical use of XR90 augmented reality-based visualization and navigation platform #
Finos K et al. · Expert review of medical devices · 2024
Interventional radiology · Narrative review
“Challenges include cost, ergonomics, rapid segmentation, and organ motion.”
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Applications and advances of immersive technology in cardiology #
Keramati H et al. · Current problems in cardiology · 2024
Adult cardiac & structural heart · Narrative review
“Our review highlights the need for a robust assessment of the effectiveness of the methods and discusses the technical limitations that hinder the complete integration of AR and VR in cardiology, including cost-effectiveness and regulatory compliance.”
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Advanced outcomes of mixed reality usage in orthognathic surgery: a systematic review #
Stevanie C et al. · Maxillofacial plastic and reconstructive surgery · 2024
Oral & maxillofacial / craniofacial · Systematic review
“The main results indicated that the use of MR technology in OGS led to high accuracy and time reduction as primary outcomes and cost-effectiveness and skill improvement as secondary outcomes.”
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Role of eXtended Reality use in medical imaging interpretation for pre-surgical planning and intraoperative augmentation #
Kantor T et al. · Journal of medical imaging (Bellingham, Wash.) · 2024
Multi-specialty · Narrative review
“However, adoption faces challenges such as high costs, infrastructure needs, and regulatory hurdles.”
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Show the other 12 studies
Application of virtual reality in dental implants: a systematic review #
Monaghesh E et al. · BMC oral health · 2023
Dental · Systematic review
“In almost all studies, the results showed that the use of virtual reality-based systems improves and enhances the skills of users, including dental students and specialists.”
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Advances in perforator imaging through holographic CTA and augmented reality: a systematic review #
Phan R et al. · Australasian Journal of Plastic Surgery · 2022
Plastic & reconstructive · Systematic review
“This, combined with a cost analysis, are the main obstructions to this technology being more widely adopted.”
DOI
[Extended reality technologies for support of surgical workflows] #
Rüger C et al. · Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
Multi-specialty · Narrative review
“In preoperative planning XR can also offer advantages, although technical limitations often impede routine use; however, for cases of intraoperative use informative evaluation studies are mostly lacking, so that an assessment is not yet possible in a meaningful way.”
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Virtual Reality in Neurosurgery: "Can You See It?"-A Review of the Current Applications and Future Potential #
Fiani B et al. · World neurosurgery · 2020
Neurosurgery · Narrative review
“In cranial surgery, VR has excelled in helping neurosurgeons design unique patient-specific approaches to particularly challenging tumor excisions.”
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Virtual and augmented reality for preoperative planning in plastic surgical procedures: A systematic review #
Vles MD et al. · Journal of plastic, reconstructive & aesthetic surgery · 2020
Plastic & reconstructive · Systematic review
“Intraoperative perforator identification in DIEP flap procedures was more accurate with AR compared to Doppler ultrasound.”
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Robotics in Pediatric Otolaryngology-Head and Neck Surgery and Advanced Surgical Planning #
Konuthula N et al. · Otolaryngologic clinics of North America · 2020
ENT / head & neck · Narrative review
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Utilising a Novel Virtual Reality System for Orthopaedic Pre-operative Trauma Planning #
Waugh D et al. · Cureus · 2025
Orthopedics · Technical report
“We have been able to demonstrate proof of functionality in what we believe is a very useful tool to aid trauma and orthopaedic pre-operative surgical planning and execution going forward.”
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Utility of Three-Dimensional Holographic Workstation for Preoperative Simulation of Complex Congenital Heart Surgery #
Takao H et al. · Interdisciplinary CardioVascular and Thoracic Surgery · 2025
Congenital heart · Case report · n: 1 patient
“The patient underwent successful biventricular repair via the Rastelli procedure and AVSD repair.”
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Novel Use of Virtual Reality and Augmented Reality in Temporomandibular Total Joint Replacement Using Stock Prosthesis #
Niloy I et al. · Journal of oral and maxillofacial surgery · 2024
Oral & maxillofacial / craniofacial · Case series · n: 2 patients
“The average differences in the positioning of the condylar and fossa prosthesis are 1.252 ± 0.269 mm and 1.393 ± 0.335 mm, respectively.”
1.252 ± 0.269 mm
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Advantages of a Training Course for Surgical Planning in Virtual Reality for Oral and Maxillofacial Surgery: Crossover Study #
Ulbrich M et al. · JMIR serious games · 2023
Oral & maxillofacial / craniofacial · Crossover study · n: 6 novices; 13 fibulae + 13 os coxae each (312 models)
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Mixed Reality and 3D Printed Models for Planning and Execution of Face Transplantation #
Cho KH et al. · Annals of surgery · 2021
Oral & maxillofacial / craniofacial · Case report · n: 1 patient
“Holographic models required less time and cost for fabrication.”
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Routine clinical application of virtual reality in abdominal surgery #
Sampogna G et al. · Minimally invasive therapy & allied technologies · 2017
General & GI surgery · Feasibility study · n: 15 patients
“Preoperative surgical planning and intraoperative guidance was feasible for all patients included in the study.”
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