Realize Medical
Research Library · Independent literature review

Spine: VR and AR surgical planning research

The library holds 26 Spine studies, published 2018–2026; 10 of them since 2024.

Study designs: 1 randomized trial, 2 comparative or prospective studies, 2 retrospective studies, 5 reviews and 16 case reports, case series and technical reports.

Spine: studies by questionBar chart. Spine: studies by question. Anatomy understanding 7, Accuracy 6, Department adoption 6, Changes the plan 5, Prefer 3D planning 3.RESEARCH LIBRARY · INDEPENDENT LITERATURE REVIEWSpine: studies by question26 studies in the libraryAnatomy understanding7Accuracy6Department adoption6Changes the plan5Prefer 3D planning3Positive findingMixedDescriptiveNo significant differenceRealize Medical Research Library · 631 studies · updated 2026-10-03

Key findings by question

Quoted from the studies. Each question lists the studies that report on it.

Do surgeons actually want to plan in 3D?

Of 3 studies with a finding on this question: 3 report a positive finding. These reflect what each study's authors report.

  • Positive finding
    “Postoperative survey results demonstrate a positive experience among surgical team members after reviewing preoperative plans created with patient-specific 3D VR models.”

    Laskay 2024 · Case series · n: 3 patients

  • Positive finding
    “The planning time was low and the surgeon's satisfaction was high regarding the practicality of its use and the result obtained.”

    Ferràs-Tarragó 2022 · Case report · n: 1 patient

  • Positive finding
    “This system was useful for cervical and lumbar decompression for confirming the proper decompression area preoperatively.”

    Aoyama 2021 · Technical note

Does it change the surgical plan?

Of 5 studies with a finding on this question: 3 report a positive finding, 2 mixed. These reflect what each study's authors report.

  • Positive finding
    “Furthermore, surgeons selected additional anatomical structures to be traversed to reach the tumor when using VR, leading to a more precise selection of surgical approaches.”

    Nantenaina 2025 · Comparative study · n: 6 patients

  • Positive finding
    “Preoperative VR planning significantly influenced surgical recommendations…”

    McCloskey 2023 · Systematic review

  • Positive finding
    “The 3D visualization of pathological conditions resulted in correct preoperative surgical planning and less invasive surgery in all five cases.”

    Aoyama 2022 · Case series · n: 5 patients

Spine studies on this questionAll specialties

Does it improve anatomical understanding?

Of 7 studies with a finding on this question: 7 report a positive finding. These reflect what each study's authors report.

  • Positive finding
    “VR can be a promising tool for surgical planning by providing an immersive and interactive perspective that enhances understanding of anatomy.”

    Nantenaina 2025 · Comparative study · n: 6 patients

  • Positive finding
    “MR also facilitated preoperative surgical planning by improving anatomical understanding, particularly regarding the anatomy of asymmetric facets and screw trajectories.”

    Rudrappa 2026 · Case report · n: 1 patient

  • Positive finding
    “SC increases the familiarity of the patient's specific anatomy and enhances perioperative assessment.”

    Elsayed 2023 · Case report · n: 1 patient

Is the planning accurate?

Of 6 studies with a finding on this question: 4 report a positive finding, 1 mixed, 1 descriptive. These reflect what each study's authors report.

  • Positive finding
    “Several studies have suggested high levels of accuracy with their use.”

    Rudrappa 2026 · Narrative review

  • Positive finding
    “For 3 patient studies, AR-assisted pedicle screw placement accuracy ranged from 95.77% to 100% using the Gertzbein grading scale.”

    McCloskey 2023 · Systematic review

  • Positive finding
    “The AR method was non-inferior to the 2D desktop planner, with a mean error of 2.1 ± 1.4 mm.”

    Pose-Díez-de-la-Lastra 2023 · Technical development

Will my department actually use it?

Of 6 studies with a finding on this question: 3 report a positive finding, 3 descriptive. These reflect what each study's authors report.

  • Positive finding
    “Three-dimensional virtual reality-assisted surgical planning for neuronavigated sacrectomy in chordoma is useful, feasible and safe.”

    Paun 2024 · Technical note · n: 1 patient

  • Positive finding
    “Real-time communication between Microsoft HoloLens 2 and 3D Slicer is feasible and supports accurate planning for pedicle screw placement.”

    Pose-Díez-de-la-Lastra 2023 · Technical development

  • Positive finding
    “Integrating SpectoVR in daily presurgical planning is feasible and appears to enhance the surgeon’s awareness of the case.”

    Croci 2020 · Case series · n: 8 patients

Studies (26)

Development of a Virtual Reality Preoperative Planning System for Postlateral Endoscopic Lumbar Discectomy Surgery and Its Clinical Application #

Zheng C et al. · World neurosurgery · 2019

Spine · Randomized controlled trial · n: 30 patients

“The use of virtual reality can predict a surgery-related angle and distance accurately except for depth.”

DOIPubMed

Evaluating virtual reality as a tool for improving surgical planning in spinal tumors #

Nantenaina TNH et al. · International journal of computer assisted radiology and surgery · 2025

Spine · Comparative study · n: 6 patients

“Furthermore, surgeons selected additional anatomical structures to be traversed to reach the tumor when using VR, leading to a more precise selection of surgical approaches.”

DOIPubMed

Virtual Reality in Preoperative Planning of Adolescent Idiopathic Scoliosis Surgery Using Google Cardboard #

De Salvatore S et al. · Neurospine · 2021

Spine · Comparative study · n: 60 patients

“The use of VR led to a significant decrease in operative time and bleeding while increasing the surgeon's satisfaction compared to the control group.”

DOIPubMedFree full text

Retrospective Comparison of Minimally Invasive and Open Monosegmental Lumbar Fusion, and Impact of Virtual Reality on Surgical Planning and Strategy #

Zawy Alsofy S et al. · Journal of neurological surgery. Part A, Central European neurosurgery · 2021

Spine · Retrospective cohort · n: 171 patients

“Image presentation using VR significantly influenced the recommended surgical therapies (decompression only/decompression and fusion; p = 0.02), had no significant influence on the recommended fusion method (rigid/dynamic/stand-alone; p = 0.77)”

p = 0.02

DOIPubMed

Virtual Reality-Based Evaluation of Surgical Planning and Outcome of Monosegmental, Unilateral Cervical Foraminal Stenosis #

Zawy Alsofy S et al. · World neurosurgery · 2019

Spine · Retrospective cohort · n: 73 patients

“Reconstruction of pre- and postoperative 2D-CT images of the cervical spine into 3D images, and the spatial and anatomical reconstructions in VR models, can be helpful in planning surgical approaches and treatment strategies for patients with cervical foraminal stenoses”

DOIPubMed

The Emerging Reality: A Narrative Review of Virtual, Augmented, and Mixed Reality in Modern Spine Surgery #

Rudrappa S et al. · Indian Spine Journal · 2026

Spine · Narrative review

“Several studies have suggested high levels of accuracy with their use.”

DOI

Advancing Spine Surgery: Innovations for Spatial Computing Integration #

Elsayed GA et al. · World neurosurgery · 2025

Spine · Narrative review

“However, challenges remain, particularly with respect to clinical validation, cost-effectiveness, and ethical considerations.”

DOIPubMed

The Evolution of Spatial Computing in Spine Surgery: Tracing the Historical Arc to Present Day Implementation #

Elsayed GA et al. · World neurosurgery · 2025

Spine · Narrative review

DOIPubMed

Virtual and Augmented Reality in Spine Surgery: A Systematic Review #

McCloskey K et al. · World neurosurgery · 2023

Spine · Systematic review

“Preoperative VR planning significantly influenced surgical recommendations…”

DOIPubMed

Augmented and virtual reality in spine surgery, current applications and future potentials #

Ghaednia H et al. · The spine journal · 2021

Spine · Narrative review

DOIPubMedFree full text

Patient-Specific Computed Tomography-Based Three-Dimensional Spine Trauma Models for Preoperative Planning in Virtual Reality and 3D Printing: An EANS Young Neurosurgeons' Network Study #

Trandzhiev M et al. · Journal of neurological surgery. Part A, Central European neurosurgery · 2026

Spine · Technical development · n: 37 patient models

DOIPubMed

Resection of C3 osteochondroma in a 20-year-old male with the combination of virtual reality and 3D printing for preoperative planning: illustrative case #

Abbas A et al. · Journal of neurosurgery. Case lessons · 2026

Spine · Case report · n: 1 patient

“Complete tumor resection was achieved without neurological or vascular complications and without breach of the upper aerodigestive tract, with complete resolution of dysphagia and no recurrence at the 3-month follow-up.”

DOIPubMedFree full text

Mixed Reality-Assisted Surgical Planning and Patient Education in a Complex Craniovertebral Junction Anomaly: A Case Report #

Rudrappa S et al. · International journal of spine surgery · 2026

Spine · Case report · n: 1 patient

“Using MR, the patient and family were counseled about the need for surgery.”

DOIPubMedFree full text

Utilizing virtual reality for resection of recurrent ventral, extramedullary cervical meningioma #

Rajendran R et al. · Surgical neurology international · 2025

Spine · Case report · n: 1 patient

DOIPubMedFree full text

Optimizing Surgical Efficiency in Complex Spine Surgery Using Virtual Reality as a Communication Technology to Promote a Shared Mental Model: A Case Series and Review #

Laskay NMB et al. · Operative neurosurgery (Hagerstown, Md.) · 2024

Spine · Case series · n: 3 patients

“Postoperative survey results demonstrate a positive experience among surgical team members after reviewing preoperative plans created with patient-specific 3D VR models.”

DOIPubMed

Three-dimensional virtual reality-assisted surgical planning for neuronavigated sacrectomy of a chordoma: a technical note #

Paun L et al. · International orthopaedics · 2024

Spine · Technical note · n: 1 patient

“Three-dimensional virtual reality-assisted surgical planning for neuronavigated sacrectomy in chordoma is useful, feasible and safe.”

DOIPubMedFree full text

Real-time integration between Microsoft HoloLens 2 and 3D Slicer with demonstration in pedicle screw placement planning #

Pose-Díez-de-la-Lastra A et al. · International journal of computer assisted radiology and surgery · 2023

Spine · Technical development

“The AR method was non-inferior to the 2D desktop planner, with a mean error of 2.1 ± 1.4 mm.”

2.1 ± 1.4 mm

DOIPubMedFree full text

Spatial Computing for preoperative planning and postoperative evaluation of single-position lateral approaches in spinal revision surgery #

Elsayed GA et al. · Journal of craniovertebral junction & spine · 2023

Spine · Case report · n: 1 patient

“SC increases the familiarity of the patient's specific anatomy and enhances perioperative assessment.”

DOIPubMedFree full text

Realidad mixta en Hololens 2 como sistema de asistencia intraoperatoria en cirugía de escoliosis idiopática del adolescente: un caso clínico #

Ferràs-Tarragó J et al. · Revista Española de Cirugía Osteoarticular · 2022

Spine · Case report · n: 1 patient

“The planning time was low and the surgeon's satisfaction was high regarding the practicality of its use and the result obtained.”

DOI

Virtual reality surgical planning for endoscopic endonasal approaches to the craniovertebral junction #

Filimonov A et al. · American journal of otolaryngology · 2022

Spine · Case series · n: 5 patients

“Such models help in the development of safe surgical plans by predicting inferior and lateral planes of dissection and assisting in the identification of critical structures.”

DOIPubMed

Show the other 6 studies

A Novel Technique of Mixed Reality Systems in the Treatment of Spinal Cord Tumors #

Aoyama R et al. · Cureus · 2022

Spine · Case series · n: 5 patients

“The 3D visualization of pathological conditions resulted in correct preoperative surgical planning and less invasive surgery in all five cases.”

DOIPubMedFree full text

Augmented Reality Device for Preoperative Marking of Spine Surgery Can Improve the Accuracy of Level Identification #

Aoyama R et al. · Spine surgery and related research · 2022

Spine · Technical note

“Without an HMD, the misidentification rate of the level was at 26.5%, while with it, the rate was reduced to 14.3%.”

14.3%

DOIPubMedFree full text

Case report: Resection of a massive primary sacrococcygeal mature teratoma in an adult using 3-dimensional reconstruction and mixed reality technology #

Zhang H et al. · Frontiers in surgery · 2022

Spine · Case report · n: 1 patient

“The 3-dimensional reconstruction and mixed reality (MR) technology based on computed tomography can provide spatial visualization, which allows surgeons to examine the teratoma at different angles preoperatively.”

DOIPubMedFree full text

The Utility of Augmented Reality in Spinal Decompression Surgery Using CT/MRI Fusion Image #

Aoyama R et al. · Cureus · 2021

Spine · Technical note

“This system was useful for cervical and lumbar decompression for confirming the proper decompression area preoperatively.”

DOIPubMedFree full text

Novel patient-specific 3D-virtual reality visualisation software (SpectoVR) for the planning of spine surgery: a case series of eight patients #

Croci DM et al. · BMJ Innovations · 2020

Spine · Case series · n: 8 patients

“Whereas VR did not omit the need for viewing the spine in the multiplane reconstruction mode, the authors feel that SpectoVR contributed to a better holistic understanding of the anatomy.”

DOI

Mixed Reality Technology Launches in Orthopedic Surgery for Comprehensive Preoperative Management of Complicated Cervical Fractures #

Wu X et al. · Surgical Innovation · 2018

Spine · Letter (experience report)

DOIPubMed

Browse the whole library

Summarises published research on VR/AR surgical planning across all platforms. Not product labelling. For Elucis indications see /elucis.

Intended for healthcare professionals.

Summaries and quotes describe each study's methods and the findings its authors report. They are not claims by Realize Medical and may contain errors: please read the original paper. Inclusion is not an endorsement of any product or use.