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Research Library · Independent literature review

Are there randomized trials of VR surgical planning?

14 studies in the library address this question.

Short answer

Yes. The library lists 14 randomized trials, from 2019 to 2026, in areas including urology, cardiology, plastic surgery and spine. Examples are Shirk 2019 and Shirk 2022 in robotic prostatectomy, Cumpanas 2025 in kidney stone surgery, Kanschik 2026 in TAVI and Garg 2025 in structural heart interventions. Most are small or add VR to standard planning, and they measure different endpoints, so they are best read one at a time.

Are there randomized trials of VR surgical planning?Bar chart. Are there randomized trials of VR surgical planning?. Urology 5, Congenital heart 2, Plastic & reconstructive 2, Adult cardiac & structural 1, Anesthesia & pain 1, ENT / head & neck 1, Oral & maxillofacial 1, Spine 1.RESEARCH LIBRARY · INDEPENDENT LITERATURE REVIEWAre there randomized trials of VRsurgical planning?14 studies in the library, by specialtyUrology5Congenital heart2Plastic & reconstructive2Adult cardiac & structur…1Anesthesia & pain1ENT / head & neck1Oral & maxillofacial1Spine1StudiesRealize Medical Research Library · 631 studies · updated 2026-10-03

How strong is the evidence?

Study designs: 14 randomized trials.

Counts come from the studies' own design labels in the library.

By specialty

Specialties with enough studies link to a page for that specialty and question.

Studies (14)

Robot-assisted Partial Nephrectomy with and without Mixed Reality - REALITATEM study #

Duarte DM Junior et al. · International braz j urol · 2026

Urology · Randomized controlled trial · n: 45 patients

“Analyses indicated statistically significant difference in ischemia time favoring RG (p = 0.045), with a mean difference of 3.8 minutes.”

p = 0.045

DOIPubMedFree full text

Randomized crossover study of immersive planning in craniomaxillofacial trauma comparing virtual reality and workstation workflows #

Pargätzi GY et al. · Scientific reports · 2026

Oral & maxillofacial / craniofacial · Randomized crossover · n: 15 participants; 5 CT datasets · Used Elucis

“Both platforms received equivalent ratings for anatomical structure recognition and physical fatigue.”

DOIPubMedFree full text

Impact of Virtual Reality on Transcatheter Aortic Valve Implantation: A Prospective Randomized Controlled Trial #

Kanschik D et al. · Circulation. Cardiovascular imaging · 2026

Adult cardiac & structural heart · Randomized controlled trial · n: 140 patients

“VR was superior to 3mensio software with respect to the 3-dimensional understanding (P<0.001).”

P<0.001

DOIPubMed

Patient-Specific Virtual Reality Rehearsal for Technically Challenging Lumbar Transforaminal Epidural Steroid Injection: A Pilot Randomized Controlled Trial #

Kim S et al. · Journal of pain research · 2026

Anesthesia & pain · Randomized controlled trial · n: 30 patients

“Procedure time was shorter in the VR group than in the control group (215.7 ± 46.8 sec vs 254.5 ± 50.3 sec; mean difference, -38.9 sec; 95% CI, -75.2 to -2.5; p = 0.037).”

p = 0.037

DOIPubMedFree full text

Preoperative Immersive Virtual Reality Applied to Percutaneous Nephrolithotomy: A Prospective Randomized Clinical Study of Surgical Planning and Clinical Outcomes #

Cumpanas AD et al. · The Journal of urology · 2025

Urology · Randomized controlled trial · n: 175 patients

“Preoperative visualization of the iVR model resulted in a changed calyx of entry in 30% of cases.”

30%

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A Randomized Pilot Trial of Virtual Reality Surgical Planning for Head and Neck Oncologic Resection #

Nunes KL et al. · The Laryngoscope · 2025

ENT / head & neck · Randomized controlled trial · n: 34 patients

“VRCEP was associated with decreased defect-driven margins (10% vs. 53.3%, p = 0.032).”

p = 0.032

DOIPubMed

Comparison between mixed reality with artificial algorithms and ultrasound in localization of anterior thigh flap perforators: a prospective randomized controlled study #

Liu Y et al. · BMC Medicine · 2025

Plastic & reconstructive · Randomized controlled trial · n: 80 patients

“Recognition rates were 94.3% in the MR group and 82.0% in the CDU group (P = 0.008).”

P = 0.008

DOIPubMedFree full text

Utility of virtual reality imaging to guide complex structural cardiac interventions: A randomized controlled trial #

Garg I et al. · Annals of pediatric cardiology · 2025

Congenital heart · Randomized controlled trial · n: 40 patients

“Adding VR reduced plan deviations and was comparable to those of the senior cardiologist (P = 0.233), indicating enhanced understanding by an early-career operator.”

P = 0.233

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Exploring the Clinical Benefits of Mixed-Reality Technology for Breast Lumpectomy #

Zhang Y et al. · Mathematical Problems in Engineering · 2023

Plastic & reconstructive · Randomized controlled trial · n: 58 patients

“In addition, doctors were significantly more satisfied with surgical planning and intraoperative localization when the MR technique was used (T = 8.273; P < 0.01 ).”

T = 8.273

DOI

Mixed Reality: A Step Further for Planning Complex Renal Tumors (RENAL Nephrometry Score of 7 or Higher) #

Yang Y et al. · Journal of endourology · 2022

Urology · Randomized controlled trial · n: 92 patients

“For urologists treating complex renal tumors, MR technology can help them reduce the warm ischemia time (21.3 ± 4.0 vs 23.6 ± 5.9 minutes, p = 0.031), reconstruction time (15.4 ± 3.8 vs 17.2 ± 4.2 minutes, p = 0.034)”

p = 0.031

DOIPubMed

Effect of 3-Dimensional, Virtual Reality Models for Surgical Planning of Robotic Prostatectomy on Trifecta Outcomes: A Randomized Clinical Trial #

Shirk JD et al. · The Journal of urology · 2022

Urology · Randomized controlled trial · n: 92 patients

“In 32% of intervention cases, the surgeons modified their operative plan based on the model.”

32%

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Mixed-reality hologram for diagnosis and surgical planning of double outlet of the right ventricle: a pilot study #

Ye W et al. · Clinical radiology · 2021

Congenital heart · Randomized controlled trial · n: 34 patients

“In the MRHG group, the 3D hologram observation was in concordance with the actual anatomical findings, and the DORV type was classified accurately in all patients.”

DOIPubMed

Development of a Virtual Reality Preoperative Planning System for Postlateral Endoscopic Lumbar Discectomy Surgery and Its Clinical Application #

Zheng C et al. · World neurosurgery · 2019

Spine · Randomized controlled trial · n: 30 patients

“The use of virtual reality can predict a surgery-related angle and distance accurately except for depth.”

DOIPubMed

Effect of 3-Dimensional Virtual Reality Models for Surgical Planning of Robotic-Assisted Partial Nephrectomy on Surgical Outcomes: A Randomized Clinical Trial #

Shirk JD et al. · JAMA network open · 2019

Urology · Randomized controlled trial · n: 92 patients

“When controlling for case complexity and other covariates, patients whose surgical planning involved 3-D VR models showed differences in operative time (odds ratio [OR], 1.00; 95% CI, 0.37-2.70; estimated OR, 2.47), estimated blood loss (OR, 1.98; 95% CI, 1.04-3.78; estimated OR, 4.56), clamp time (OR, 1.60; 95% CI, 0.79-3.23; estimated OR, 11.22), and length of hospital stay (OR, 2.86; 95% CI, 1.59-5.14; estimated OR, 5.43).”

DOIPubMedFree full text

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Summarises published research on VR/AR surgical planning across all platforms. Not product labelling. For Elucis indications see /elucis.

Intended for healthcare professionals.

Summaries and quotes describe each study's methods and the findings its authors report. They are not claims by Realize Medical and may contain errors: please read the original paper. Inclusion is not an endorsement of any product or use.