Elucis and VR Clinical Validation in Medicine
Select a specialty or clinical benefit below to filter results. Cards marked "Elucis Clinical Data" used Elucis by Realize Medical as the VR platform.
Showing 35 studies·18 with Elucis Clinical Data
In patients where conventional CT and echocardiography failed to resolve a management dilemma, Elucis VR changed the clinical management decision in 70% of complex congenital heart disease cases.
Tiwari et al., 2025 — Med J Armed Forces India
Prospective StudyElucis VR achieved equivalent segmentation quality (DICE 96%) as desktop software while being up to 42% faster, with a dramatically higher usability score (83.3 vs 30.4) and a statistically significant learning curve — surgeons improved substantially with VR practice but not with desktop tools.
Ulbrich et al., 2023 — JMIR Serious Games
Crossover StudyElucis-generated VR models predicted the correct vascular access site in 85.7% of neonatal PDA stenting cases, with stent size within one category in 88.1% of cases. Inter-rater measurement reliability ICC exceeded 0.977.
Saini et al., 2025 — Pediatric Cardiology
Retrospective StudyVR patient screening for self-expanding pulmonary valves in Elucis achieved 96.3% accuracy versus 85.2% from manufacturer analysis, with 100% specificity for correctly ruling out non-candidates.
Zablah et al., 2024 — Journal of the American Heart Association
Retrospective StudyElucis VR simulation correctly predicted the presence or absence of paravalvular leak in 100% of bicuspid aortic valve TAVR cases (n=22), with a ROC AUC of 0.83 for malapposition prediction.
Chahine et al., 2024 — Radiology
Retrospective StudyVR mandible segmentation in Elucis achieved 96.8% DICE precision — outperforming AI methods — while being 24% faster than desktop tools (15.9 vs 21.0 min), with superior anatomical perception ratings.
Gruber et al., 2024 — J Oral Maxillofac Surg
Observational StudyMRI-based VR screening in Elucis identified 4 TPVR candidates who had been excluded by industry CT-based screening criteria — all 4 underwent successful valve implantation. Standard screening criteria alone may systematically exclude suitable patients.
Wilson et al., 2026 — Cardiology in the Young
Retrospective StudyElucis-measured valve frame geometry (perimeter ≥125.2 mm) predicted clinically significant ventricular arrhythmia after self-expanding transcatheter pulmonary valve replacement with 87.5% sensitivity, demonstrating that VR-based sizing data carries risk stratification value beyond implant selection.
Soszyn et al., 2025 — Pediatric Cardiology
Retrospective StudyElucis VR reduced craniospinal target volume contouring time by 50% compared to standard desktop platforms, with equivalent accuracy (DICE similarity coefficient 0.96–0.99) and high user preference.
Belec et al., 2024 — Pilot validation study
Pilot StudyTen consecutive congenital cardiac interventions planned in Elucis — spanning PDA stenting, transcatheter pulmonary valve replacement, and coarctation stenting in patients aged 5 days to 42 years — all completed successfully with zero major complications.
Tailor et al., 2023 — Congenital Heart Disease
Pilot SeriesElucis enabled real-time collaborative VR sessions between institutions for complex congenital interventions, including virtual "fly-through" of patient vasculature, device simulation, and pre-identification of procedural complications.
Salavitabar et al., 2024 — JSCAI
Case SeriesElucis 3D modeling enabled planning of a combined heart-liver transplant in a patient with situs inversus and dextrocardia — a case where conventional imaging had been unable to provide sufficient anatomical clarity.
Ganigara et al., 2025 — J Am Heart Assoc
Case Report4D VR segmentation in Elucis across 10 cardiac phases demonstrated RVOT apposition throughout the cardiac cycle, directly guiding successful transcatheter pulmonary valve deployment with no post-procedure leak.
Wilson et al., 2025 — Pediatric Cardiology
Case ReportElucis VR planning guided embolization of three simultaneous pulmonary arteriovenous malformations — the first reported use of 3D technologies for this procedure — restoring oxygen saturation from 89% to 96–98%.
Gurav et al., 2024 — JACC Case Reports
Case ReportElucis VR simulation of a complex fully-endophytic renal mass enabled pre-operative identification of critical vascular territories, achieving 22 minutes warm ischemia time and 75 cc estimated blood loss.
Schulder et al., 2025 — Journal of Urology
Case ReportAdvanced imaging with expert-guided ultrasonography and magnetic resonance imaging (MRI) is recommended for noninvasive endometriosis, with MRI preferred for mapping complex endometriosis lesions with extrapelvic involvement.
Sukhbir S. Singh, Shauna Duigenan, Layli Tanara, and Teresa E. Flaxman. CMAJ, May 11, 2026, 198 (18) E698-E703; DOI: https://doi.org/10.1503/cmaj.241889
Case ReportElucis VR generated a patient-specific 3D model from preoperative MRI in approximately 35 minutes for a complex deep endometriosis case (70% bowel wall invasion), enabling the surgical team to visualize and rehearse anatomy before successful laparoscopic excision with low anterior resection.
Cooke et al., 2023 — J Obstet Gynaecol Can
Case ReportElucis VR-derived 3D modeling guided pre-procedural planning for transcatheter closure of a rare right pulmonary artery–left atrium fistula, with multi-modality image fusion guiding successful percutaneous closure and normalization of oxygen saturation to 94% on room air — the first reported use of fusion imaging for this lesion type.
Soszyn et al., 2024 — Cardiology in the Young
Case ReportIn a randomized controlled trial of 175 patients, preoperative immersive VR planning for percutaneous nephrolithotomy significantly improved stone-free rate (34% vs 20%), reduced complications (3.5% vs 12.3%), and saved 115 minutes of OR time.
Cumpanas et al., 2024 — J Urology
RCTIn a randomized controlled trial of 34 head and neck cancer resections, VR-based preoperative planning reduced the margin event rate from 40.0% to 11.6% (p=0.004), with 100% of surgeons reporting VR was easily integrated and helpful.
Nunes et al., 2025 — Laryngoscope
RCTVirtual surgical planning for mandibular condylar fractures improved anatomic reduction rate from 68.6% to 90.6% at one week (p=0.027), reduced deviation from 0.995 mm to 0.639 mm, and shortened OR time by 42 minutes.
Shakya et al., 2022 — Chin J Traumatol
RCTA systematic review of 733 patients found VR surgical planning saved a mean 73.8 minutes of OR time (p=0.008), with 78% of studies finding VR planning cost-neutral or cost-saving vs traditional planning.
Xiao et al., 2025 — Head Neck
Systematic ReviewSystematic review evidence across specialties shows VR preoperative planning can reduce intraoperative blood loss (133 vs 259 mL, p=0.023) and fluoroscopy time (180s vs 226s), with anatomy visualization improved in 67% of studies.
Lan et al., 2023 — Ann Surg
Systematic ReviewMeta-analysis of 370 otolaryngology patients found VR reduced procedural anxiety with a large effect size (Cohen's d = 0.84), alongside meaningful improvements in pain (d = 0.36) and patient satisfaction (d = 0.55).
Do et al., 2025 — Laryngoscope
Meta-analysisVR review of preoperative anatomy led urologists to alter their planned approach in 40% of robotic partial nephrectomy cases, including identifying vascular anatomy missed entirely on standard cross-sectional imaging.
McDonald & Shirk, 2021 — JSLS
Prospective StudyVR preoperative modeling for complex surgical oncology (liver, pancreas, retroperitoneum) improved operating surgeon concordance between planned and actual surgery from 54% to 92%, with surgical plan changes in 42% of cases.
Lyuksemburg et al., 2023 — Ann Surg Oncol
Prospective StudySurgeons performing cerebrovascular procedures found VR effective for understanding complex 3D anatomy in 83.3% of cases, with surgical technique decisions influenced in 61.1% of cases and favorable outcomes in 94.4% of patients.
Sugiyama et al., 2021 — Oper Neurosurg
Prospective StudyVR-based case review for complex congenital heart disease reduced surgeons' perceived mental demand by half compared to traditional 2D surgical conference review (median 3/10 vs 6/10, p=0.016), while significantly increasing confidence in anatomical understanding (p=0.012). Eight of 10 sessions ended with surgeons expressing spontaneous excitement about the anatomy.
Bethke et al., 2025 — Int J Comput Assist Radiol Surg
Prospective StudyVR preoperative planning for microsurgical middle cerebral artery aneurysm clipping reduced mean procedure time from 120 to 40 minutes — an 80-minute reduction — with 100% successful aneurysm obliteration and no perioperative complications.
Steineke & Barbery, 2021 — Neurosurg Focus
Retrospective StudyAneurysm surgery planned with 3D VR achieved 97.4% good outcomes (mRS ≤2) for unruptured aneurysms with 0% mortality across 105 patients, comparable to international benchmarks — and trainee-performed cases yielded 100% good outcomes.
Kockro et al., 2016 — World Neurosurg
Retrospective StudyAcross 158 medical professionals — surgeons, residents, students, and nurses — 94.3% agreed that complex surgical cases could be assessed better with VR, and 84.8% found it faster than standard imaging review.
Kenngott et al., 2022 — Surg Endosc
Observational StudyVR-guided preoperative planning for intracranial tumors achieved gross total resection in 85% of cases with an average VR review time of just 9.5 minutes, across 49 patients at 5 institutions.
Louis et al., 2021 — Oper Neurosurg
Retrospective StudyIn orthopedic surgery, 3D VR planning reduced OR time and blood loss in complex fracture fixation (66.5 vs 75.4 min; 41.1 vs 54.2 mL), while VR-trained surgeons achieved 90% correct-grade pedicle screw placement versus 37.5% in conventionally trained controls.
Portnoy et al., 2023 — Int J Surg
Narrative ReviewAR and VR guidance for pedicle screw instrumentation in spinal surgery reduced misplacement from 8.9% to 4.3% (p<0.05) and operative time by up to 20%, across a systematic review of more than 850 patients. Deviation was reduced from 4.5 mm to 1.2 mm in direct comparison studies.
Xiao et al., 2024 — Medicina
Narrative ReviewImmersive 3D VR planning for minimally invasive and complex adult cardiac surgery achieved 100% surgical success with zero intraoperative complications across 6 high-complexity cases, rated 4.4/5 for clinical usefulness.
Sadeghi et al., 2020 — Innovations
Case Series