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Research Library · Independent literature review

Plastic & reconstructive: VR and AR surgical planning research

The library holds 36 Plastic & reconstructive studies, published 2017–2026; 16 of them since 2024.

Study designs: 2 randomized trials, 2 comparative or prospective studies, 10 reviews and 22 case reports, case series and technical reports.

Plastic & reconstructive: studies by questionBar chart. Plastic & reconstructive: studies by question. Accuracy 14, Time 10, Prefer 3D planning 8, Department adoption 8, Anatomy understanding 7, Patient outcomes 4.RESEARCH LIBRARY · INDEPENDENT LITERATURE REVIEWPlastic & reconstructive: studies byquestion36 studies in the libraryAccuracy14Time10Prefer 3D planning8Department adoption8Anatomy understanding7Patient outcomes4Positive findingMixedDescriptiveNo significant differenceRealize Medical Research Library · 631 studies · updated 2026-10-03

Key findings by question

Quoted from the studies. Each question lists the studies that report on it.

Do surgeons actually want to plan in 3D?

Of 8 studies with a finding on this question: 5 report a positive finding, 3 descriptive. These reflect what each study's authors report.

  • Positive finding
    “In addition, doctors were significantly more satisfied with surgical planning and intraoperative localization when the MR technique was used (T = 8.273; P < 0.01 ).”

    Zhang 2023 · Randomized controlled trial · n: 58 patients

  • Positive finding
    “Overall, preoperative planning using VR was easy to use, safe, more intuitive, and provided in a time-efficient manner, more information about perforant characteristics.”

    Di Via Ioschpe 2023 · Validation study · n: 44 patients

  • Positive finding
    “The findings indicate that AI-enhanced 3D imaging and immersive virtual communication platforms are valuable tools for integrative surgical case assessments.”

    Obst 2025 · Feasibility study · n: 15 patients

Does it improve anatomical understanding?

Of 7 studies with a finding on this question: 3 report a positive finding, 4 descriptive. These reflect what each study's authors report.

  • Positive finding
    “Using different visualization settings, the spatial relationship of perforators to surrounding anatomical structures-especially the subcutaneous tissue and the Rectus Abdominis Muscle-can be understood more intuitively.”

    Necker 2026 · Technical development

  • Positive finding
    “The surgeons ranked VR higher than CTA in terms of better anatomical understanding and operative anatomical findings.”

    Freidin 2023 · Case series · n: 30 patients

  • Positive finding
    “The combination of Horos and Elements allows a better understanding of the ALT-free flap anatomy to virtually plan the surgery and to transfer the digital data to the Magic Leap Headset.”

    Heredero 2022 · Technical note · n: 6 patients

Does it save time?

Of 10 studies with a finding on this question: 8 report a positive finding, 2 descriptive. These reflect what each study's authors report.

Randomized trials: 1 trial on this question; 1 reported a positive finding.

  • Positive finding
    “Flap harvest times averaged 52 and 68 min, respectively (P < 0.0001).”

    Liu 2025 · Randomized controlled trial · n: 80 patients

  • Positive finding
    “The MRI analysis time was significantly lower with the DIVA system than with the slice-based visualization for residents, practitioners, and subsequently the entire group (P < .001).”

    El Beheiry 2021 · Comparative study

  • Positive finding
    “XR use decreased operative time, with AR reducing intraoperative perforator localization time from 20 min using handheld Doppler US to 2.3 min.”

    Zijlstra 2026 · Systematic review

Plastic & reconstructive studies on this questionAll specialties

Is the planning accurate?

Of 14 studies with a finding on this question: 9 report a positive finding, 2 mixed, 3 no significant difference. These reflect what each study's authors report.

  • Positive finding
    “Recognition rates were 94.3% in the MR group and 82.0% in the CDU group (P = 0.008).”

    Liu 2025 · Randomized controlled trial · n: 80 patients

  • Positive finding
    “A correlation was found between the imaging modalities for unilateral (R = 0.96 (CI = 0.92, 0.98)) and bilateral (R = 0.93, (CI = 0.83, 0.97)) DIEP flap surgeries when comparing perforator location related to the umbilicus.”

    Di Via Ioschpe 2023 · Validation study · n: 44 patients

  • Positive finding
    “XR technologies were associated with improved accuracy in perforator identification, reduced operating times, and enhanced surgical planning.”

    Ozmen 2025 · Systematic review

Does it affect patient outcomes?

Of 4 studies with a finding on this question: 2 descriptive, 2 no significant difference. These reflect what each study's authors report.

  • Descriptive
    “In the MR group, one flap developed an infection and another necrosis, while in the CDU group, one flap had a crisis, and two experienced necrosis.”

    Liu 2025 · Randomized controlled trial · n: 80 patients

  • Descriptive
    “There were no complications during the postoperative course.”

    Nuri 2022 · Case report · n: 1 patient

All specialties

Will my department actually use it?

Of 8 studies with a finding on this question: 2 report a positive finding, 6 descriptive. These reflect what each study's authors report.

  • Positive finding
    “Our technique can be performed by surgeons independently with a laptop and a Microsoft HoloLens, making CT angiography data more accessible and practical for use in plastic surgery.”

    Necker 2026 · Technical development

  • Positive finding
    “While the study demonstrates the feasibility of this approach, further research is needed to explore a broader application and impact of these technologies in global health.”

    Obst 2025 · Feasibility study · n: 15 patients

  • Descriptive
    “While preliminary results are promising, further large-scale studies are needed to establish efficacy, address limitations, and facilitate integration into clinical practice.”

    Ozmen 2025 · Systematic review

Studies (36)

Comparison between mixed reality with artificial algorithms and ultrasound in localization of anterior thigh flap perforators: a prospective randomized controlled study #

Liu Y et al. · BMC Medicine · 2025

Plastic & reconstructive · Randomized controlled trial · n: 80 patients

“Recognition rates were 94.3% in the MR group and 82.0% in the CDU group (P = 0.008).”

P = 0.008

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Exploring the Clinical Benefits of Mixed-Reality Technology for Breast Lumpectomy #

Zhang Y et al. · Mathematical Problems in Engineering · 2023

Plastic & reconstructive · Randomized controlled trial · n: 58 patients

“In addition, doctors were significantly more satisfied with surgical planning and intraoperative localization when the MR technique was used (T = 8.273; P < 0.01 ).”

T = 8.273

DOI

Preoperative planning using virtual reality and computed tomography angiogram in deep inferior epigastric perforator flap breast reconstruction #

Di Via Ioschpe A et al. · Journal of plastic, reconstructive & aesthetic surgery · 2023

Plastic & reconstructive · Validation study · n: 44 patients

“A correlation was found between the imaging modalities for unilateral (R = 0.96 (CI = 0.92, 0.98)) and bilateral (R = 0.93, (CI = 0.83, 0.97)) DIEP flap surgeries when comparing perforator location related to the umbilicus.”

R = 0.96

DOIPubMed

Breast Magnetic Resonance Image Analysis for Surgeons Using Virtual Reality: A Comparative Study #

El Beheiry M et al. · JCO clinical cancer informatics · 2021

Plastic & reconstructive · Comparative study

“The MRI analysis time was significantly lower with the DIVA system than with the slice-based visualization for residents, practitioners, and subsequently the entire group (P < .001).”

P < .001

DOIPubMed

Extended reality for perforator visualization in deep inferior epigastric perforator autologous breast reconstruction: A systematic review #

Zijlstra K et al. · JPRAS open · 2026

Plastic & reconstructive · Systematic review

“XR use decreased operative time, with AR reducing intraoperative perforator localization time from 20 min using handheld Doppler US to 2.3 min.”

2.3 min

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Extended Reality Technologies for Visualization in DIEP Flap Breast Reconstruction: A Systematic Review #

Ozmen BB et al. · Surgical innovation · 2025

Plastic & reconstructive · Systematic review

“XR technologies were associated with improved accuracy in perforator identification, reduced operating times, and enhanced surgical planning.”

DOIPubMed

Extended reality for mapping perforator-based flaps in breast reconstruction: a systematic review and meta-analysis #

Lacey H et al. · JPRAS open · 2025

Plastic & reconstructive · Systematic review

“Preoperative VR was associated with shorter operative times than conventional Doppler ultrasound (478±56.94 vs 606.29 ± 81.94 min, P<0.05).”

P<0.05

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The Role of Virtual Reality, Augmented Reality and Mixed Reality in Modernizing Free Flap Reconstruction Techniques #

Heredero S et al. · Oral and maxillofacial surgery clinics of North America · 2025

Plastic & reconstructive · Narrative review

DOIPubMed

The use of extended reality in microsurgical free flap planning - A systematic review #

Rasmussen KH et al. · JPRAS open · 2025

Plastic & reconstructive · Systematic review

“Virtual reality demonstrated better visualization of patient-specific anatomy and was more time efficient than CT angiography.”

DOIPubMedFree full text

From Augmented to Virtual Reality in Plastic Surgery: Blazing the Trail to a New Frontier #

Sullivan J et al. · Journal of reconstructive microsurgery · 2024

Plastic & reconstructive · Narrative review

“VR has been shown to increase surgical precision and decrease operative time.”

DOIPubMed

Advances in perforator imaging through holographic CTA and augmented reality: a systematic review #

Phan R et al. · Australasian Journal of Plastic Surgery · 2022

Plastic & reconstructive · Systematic review

“This, combined with a cost analysis, are the main obstructions to this technology being more widely adopted.”

DOI

Virtual and augmented reality for preoperative planning in plastic surgical procedures: A systematic review #

Vles MD et al. · Journal of plastic, reconstructive & aesthetic surgery · 2020

Plastic & reconstructive · Systematic review

“Intraoperative perforator identification in DIEP flap procedures was more accurate with AR compared to Doppler ultrasound.”

DOIPubMedFree full text

The New Frontier: A Review of Augmented Reality and Virtual Reality in Plastic Surgery #

Sayadi LR et al. · Aesthetic surgery journal · 2019

Plastic & reconstructive · Systematic review

DOIPubMed

Virtual Reality and Augmented Reality in Plastic Surgery: A Review #

Kim Y et al. · Archives of plastic surgery · 2017

Plastic & reconstructive · Systematic review

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Holographic Deep Inferior Epigastric Perforator Exploration in Mixed Reality using Real-Time Cinematic Rendering #

Necker FN et al. · Aesthetic plastic surgery · 2026

Plastic & reconstructive · Technical development

“Using different visualization settings, the spatial relationship of perforators to surrounding anatomical structures-especially the subcutaneous tissue and the Rectus Abdominis Muscle-can be understood more intuitively.”

DOIPubMed

814 Evaluation of Mixed Reality for Burn Margin Visualization and Surgical Planning #

Journal of burn care & research · 2025

Plastic & reconstructive · Conference abstract

“When the traces were aligned with the ground truth using ICP, the pass-through headset had the highest IOU (0.797), followed by the see-through headset (0.770), with both outperforming the control condition (0.763) in trace precision.”

0.797

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Augmented reality in preoperative anterolateral thigh flap perforators positioning: A pilot diagnostic study #

Wei B et al. · Oral oncology · 2025

Plastic & reconstructive · Diagnostic accuracy study · n: 24 patients

“AR-Finder demonstrated a higher sensitivity of 97.5 % (95 % CI 85.3 %-99.9 %, p = 0.031) and an AUC of 0.90 (95 % CI 0.80-1.01, p = 0.035).”

97.5 %

DOIPubMed

AI-Enhanced 3D Models in Global Virtual Reality Case Conferences for Surgical Care in a Low-Income Country: Exploratory Study #

Obst M et al. · JMIR formative research · 2025

Plastic & reconstructive · Feasibility study · n: 15 patients

“The process was time-efficient, with a total of under 8 minutes per case for data acquisition and model creation, and resource-efficient with surgeons reporting sufficient quality of smartphone-derived models.”

8 minutes

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Design and evaluation of an AR-based thermal imaging system for planning reconstructive surgeries #

Unger M et al. · International journal of computer assisted radiology and surgery · 2024

Plastic & reconstructive · Technical development · n: 21 participants

“The mean projection error is 10.3 ± 9.4 mm.”

10.3 ± 9.4 mm

DOIPubMed

The Reconstructive Metaverse - Collaboration in Real-Time Shared Mixed Reality Environments for Microsurgical Reconstruction #

Necker FN et al. · Surgical innovation · 2024

Plastic & reconstructive · Technical note · n: 4 patients

“In these sessions, surgeons discuss perforator anatomy and perforator selection strategies whilst comprehensively assessing the respective models.”

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Show the other 16 studies

TARDUS: A combined method for microsurgical easy planning with Thermography, Augmented Reality and Doppler Ultrasound #

Pereira N et al. · Journal of plastic, reconstructive & aesthetic surgery · 2024

Plastic & reconstructive · Letter (no abstract)

DOIPubMed

[The use of augmented reality for preoperative preparation of perforated flaps: a pilot study] #

Shpitser IM et al. · Stomatologiia · 2024

Plastic & reconstructive · Feasibility study · n: 3 patients

“AR for microsurgical planning was performed in two inguinal regions and was 100% correlated with the results of high-frequency ultrasound, in the case of perforant vessels of the peroneal artery”

100%

DOIPubMed

BREAST+: An augmented reality interface that speeds up perforator marking for DIEAP flap reconstruction surgery #

Timóteo R et al. · Healthcare technology letters · 2024

Plastic & reconstructive · Technical development

“The average time taken to mark each perforator is 7.7 ± 6.5 s, with an average absolute error of 6.8 ± 2.6 mm and an estimated average deviation of 3.6 ± 1.4 mm.”

7.7 ± 6.5 s

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Using Virtual Reality for Deep Inferior Epigastric Perforator Flap Preoperative Planning #

Freidin D et al. · Plastic and reconstructive surgery. Global open · 2023

Plastic & reconstructive · Case series · n: 30 patients

“In four cases, VR imaging modified the surgical strategy…”

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HoloLens in Breast Reconstruction: What Is the Future? #

Masterton G et al. · Plastic and reconstructive surgery · 2023

Plastic & reconstructive · Technical note

“Although the authors did not use the HoloLens technology to make clinical decisions, they provide evidence of its accuracy and ease of use, offering a proof of concept.”

DOIPubMed

Workflow assessment of an augmented reality application for planning of perforator flaps in plastic reconstructive surgery: Game or game changer? #

Berger MF et al. · Digital health · 2023

Plastic & reconstructive · Feasibility study

“The overall usability (SUS) was 67 ± 10 (=moderate to good).”

67 ± 10

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Three-dimensional virtual reality in surgical planning for breast cancer with reconstruction #

De la Cruz-Ku G et al. · SAGE open medical case reports · 2023

Plastic & reconstructive · Case report · n: 1 patient

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Improving Visualization of Intramuscular Perforator Course: Augmented Reality Headsets for DIEP Flap Breast Reconstruction #

Seth I et al. · Plastic and reconstructive surgery. Global open · 2023

Plastic & reconstructive · Case series · n: 5 patients

“AR technology shows promise in enhancing perforator identification efficiency and deepening understanding of perforator trajectories during preoperative planning.”

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Application of augmented reality (AR) technology to locate the cutaneous perforator of anterolateral thigh perforator flap: A case report #

Nuri T et al. · Microsurgery · 2022

Plastic & reconstructive · Case report · n: 1 patient

“There were no complications during the postoperative course.”

DOIPubMed

DIEP Flap Preoperative Planning Using Virtual Reality Based on CT Angiography #

Egozi D et al. · Plastic and reconstructive surgery. Global open · 2022

Plastic & reconstructive · Technical note

“We postulate that preoperative planning by the new Amplifier VR tool can increase a surgeon’s understanding of the patient’s individual anatomy and facilitate the complex task of choosing the optimal perforator for flap harvest.”

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Virtual Planning and Mixed Reality for the Thin Anterolateral Thigh Perforator Flap #

Heredero S et al. · Plastic and reconstructive surgery. Global open · 2022

Plastic & reconstructive · Technical note · n: 6 patients

“The combination of Horos and Elements allows a better understanding of the ALT-free flap anatomy to virtually plan the surgery and to transfer the digital data to the Magic Leap Headset.”

DOIPubMedFree full text

Breast3D: An Augmented Reality System for Breast CT and MRI #

Allison B et al. · International Conference on Artificial Intelligence and Virtual Reality · 2020

Plastic & reconstructive · Technical development

DOIFree full text

The Application of Virtual Reality for Preoperative Planning of Lymphovenous Anastomosis in a Patient with a Complex Lymphatic Malformation #

Giacalone G et al. · Journal of clinical medicine · 2019

Plastic & reconstructive · Case report · n: 1 patient

“Based on the combined findings of this 3D model and lymphography with a fluorescent marker, a precise skin incision could be determined and one lymph vessel was anastomosed to a nearby vein.”

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Augmented reality mastectomy surgical planning prototype using the HoloLens template for healthcare technology letters #

Amini S, Kersten-Oertel M · Healthcare technology letters · 2019

Plastic & reconstructive · Technical development

“This method can be quicker than the traditional way and eliminates sizer implants from the process.”

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A Mixed-Reality System for Breast Surgical Planning #

Perkins SL et al. · 2017 IEEE International Symposium on Mixed and Augmented Reality (ISMAR-Adjunct) · 2017

Plastic & reconstructive · Technical development

DOI

[Identification of perforating vessels by augmented reality: Application for the deep inferior epigastric perforator flap] #

Bosc R et al. · Annales de chirurgie plastique et esthetique · 2017

Plastic & reconstructive · Technical note · n: 12 patients

DOIPubMed

Browse the whole library

Summarises published research on VR/AR surgical planning across all platforms. Not product labelling. For Elucis indications see /elucis.

Intended for healthcare professionals.

Summaries and quotes describe each study's methods and the findings its authors report. They are not claims by Realize Medical and may contain errors: please read the original paper. Inclusion is not an endorsement of any product or use.