Realize Medical
Research Library · Independent literature review

Does VR surgical planning reduce operating time?

85 studies in the library address this question.

Short answer

The time gains in the library are on specific steps. Mixed-reality planning was linked to shorter ischemia time in robot-assisted partial nephrectomy (Duarte 2026), faster flap harvest after perforator mapping (Liu 2025), shorter planning time (Ye 2021), and shorter procedure time for a spinal injection rehearsed in VR (Kim 2026). Results vary by procedure. Where trials measured total operating time, some found similar durations between groups (Shirk 2019, Cumpanas 2025), while a retrospective study reported shorter operations (Zhu 2022).

Does VR surgical planning reduce operating time?Bar chart. Does VR surgical planning reduce operating time?. Neurosurgery 19, Urology 11, Congenital heart 10, Plastic & reconstructive 10, Oral & maxillofacial 8, HPB 4, Multi-specialty 4, Adult cardiac & structural 3.RESEARCH LIBRARY · INDEPENDENT LITERATURE REVIEWDoes VR surgical planning reduceoperating time?85 studies in the library, by specialtyNeurosurgery19Urology11Congenital heart10Plastic & reconstructive10Oral & maxillofacial8HPB4Multi-specialty4Adult cardiac & structur…3Positive findingMixedDescriptiveNo significant differenceRealize Medical Research Library · 631 studies · updated 2026-10-03

How strong is the evidence?

Study designs: 8 randomized trials, 27 comparative or prospective studies, 16 retrospective studies, 4 surveys and user studies, 10 reviews and 20 case reports, case series and technical reports.

Randomized trials: 6 trials on this question; 5 reported a positive finding, 1 no significant difference.

Counts come from the studies' own design labels in the library.

By specialty

Specialties with enough studies link to a page for that specialty and question.

Studies (85)

Robot-assisted Partial Nephrectomy with and without Mixed Reality - REALITATEM study #

Duarte DM Junior et al. · International braz j urol · 2026

Urology · Randomized controlled trial · n: 45 patients

Positive finding
“Analyses indicated statistically significant difference in ischemia time favoring RG (p = 0.045), with a mean difference of 3.8 minutes.”

p = 0.045

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Patient-Specific Virtual Reality Rehearsal for Technically Challenging Lumbar Transforaminal Epidural Steroid Injection: A Pilot Randomized Controlled Trial #

Kim S et al. · Journal of pain research · 2026

Anesthesia & pain · Randomized controlled trial · n: 30 patients

Positive finding
“Procedure time was shorter in the VR group than in the control group (215.7 ± 46.8 sec vs 254.5 ± 50.3 sec; mean difference, -38.9 sec; 95% CI, -75.2 to -2.5; p = 0.037).”

p = 0.037

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Preoperative Immersive Virtual Reality Applied to Percutaneous Nephrolithotomy: A Prospective Randomized Clinical Study of Surgical Planning and Clinical Outcomes #

Cumpanas AD et al. · The Journal of urology · 2025

Urology · Randomized controlled trial · n: 175 patients

“Preoperative visualization of the iVR model resulted in a changed calyx of entry in 30% of cases.”

30%

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Comparison between mixed reality with artificial algorithms and ultrasound in localization of anterior thigh flap perforators: a prospective randomized controlled study #

Liu Y et al. · BMC Medicine · 2025

Plastic & reconstructive · Randomized controlled trial · n: 80 patients

Positive finding
“Flap harvest times averaged 52 and 68 min, respectively (P < 0.0001).”

P < 0.0001

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Utility of virtual reality imaging to guide complex structural cardiac interventions: A randomized controlled trial #

Garg I et al. · Annals of pediatric cardiology · 2025

Congenital heart · Randomized controlled trial · n: 40 patients

No difference reported
“Despite VR's potential to simplify the intervention, it did not affect procedural duration or contrast volume in this early experience.”

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Mixed Reality: A Step Further for Planning Complex Renal Tumors (RENAL Nephrometry Score of 7 or Higher) #

Yang Y et al. · Journal of endourology · 2022

Urology · Randomized controlled trial · n: 92 patients

Positive finding
“For urologists treating complex renal tumors, MR technology can help them reduce the warm ischemia time (21.3 ± 4.0 vs 23.6 ± 5.9 minutes, p = 0.031), reconstruction time (15.4 ± 3.8 vs 17.2 ± 4.2 minutes, p = 0.034)”

p = 0.031

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Mixed-reality hologram for diagnosis and surgical planning of double outlet of the right ventricle: a pilot study #

Ye W et al. · Clinical radiology · 2021

Congenital heart · Randomized controlled trial · n: 34 patients

Positive finding
“The surgical planning time was shorter for the MRHG group (51.65 ± 11.11 min) than that for the control group (65.71 ± 18.07 min, p<0.05).”

p<0.05

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Effect of 3-Dimensional Virtual Reality Models for Surgical Planning of Robotic-Assisted Partial Nephrectomy on Surgical Outcomes: A Randomized Clinical Trial #

Shirk JD et al. · JAMA network open · 2019

Urology · Randomized controlled trial · n: 92 patients

“When controlling for case complexity and other covariates, patients whose surgical planning involved 3-D VR models showed differences in operative time (odds ratio [OR], 1.00; 95% CI, 0.37-2.70; estimated OR, 2.47), estimated blood loss (OR, 1.98; 95% CI, 1.04-3.78; estimated OR, 4.56), clamp time (OR, 1.60; 95% CI, 0.79-3.23; estimated OR, 11.22), and length of hospital stay (OR, 2.86; 95% CI, 1.59-5.14; estimated OR, 5.43).”

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Impact of Mixed Reality on Middle Cerebral Artery Aneurysm Clipping: Initial Experience With 25 Cases #

Colombo E et al. · Operative neurosurgery (Hagerstown, Md.) · 2026

Neurosurgery · Comparative study · n: 50 cases (25 MxR, 25 control)

No significant difference
“The mean craniotomy diameter and mean surgical preparation time did not differ significantly.”

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Comparative evaluation of mixed reality, CTA-based digital guide, and hand-held Doppler for anterolateral thigh perforator localization in head and neck reconstruction #

Zhu H et al. · International journal of oral and maxillofacial surgery · 2026

Oral & maxillofacial / craniofacial · Comparative study · n: 12 patients

Mixed
“CTA-MR required less preparation time than guide fabrication but a longer intraoperative localization time than guide placement.”

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Mixed reality three dimensional visualization facilitates repair of posterior urethral rupture after pelvic fracture #

Hua Y et al. · Research Square · 2025

Urology · Preprint (prospective cohort) · n: 32 patients

No significant difference
“Compared with the control group, the mixed reality technology group showed an average operative time reduction of about 12 minutes, although this difference was not statistically significant (P > 0.05)”

12 minutes

DOI

Validation of mixed reality in planning orbital reconstruction with patient-specific implants #

Dubron K et al. · Scientific reports · 2025

Oral & maxillofacial / craniofacial · Comparative study · n: 10 cases

Positive finding
“The total workflow time for MR technology was significantly shorter compared to the conventional method.”

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Mixed Reality-Assisted Surgical Planning of Flow-Augmentation Extracranial-Intracranial Bypass Surgery: A Technical Note #

Colombo E et al. · World neurosurgery · 2025

Neurosurgery · Comparative study · n: 10 cases (plus matched controls)

Positive finding
“Mean holographic preparation time was 36 +/- 12 minutes.”

36 +/- 12 minutes

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Optimizing the Workflow of Superficial Temporal Artery Mapping in Extracranial-Intracranial Bypass Surgery Using Mixed Reality: A Proof-of-Concept Study #

Bhatia S et al. · World neurosurgery · 2025

Neurosurgery · Validation study · n: 7 patients

Mixed
“MR mapping of the STA was faster than Doppler mapping (11.3 ± 1.47 vs. 67.2 ± 17.6 seconds; P = 0.001).”

P = 0.001

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Benefit of virtual reality during visceral artery aneurysms open and endovascular surgery planning #

Donzel D et al. · Journal of vascular surgery cases and innovative techniques · 2025

Vascular · Comparative study · n: 10 patients

Positive finding
“The learning curve is short, and the analysis process is not time consuming.”

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The potential of Real-Time rendered-volume 3D Imaging in immersive virtual-reality (VR) for surgical planning in infants with congenital thoracic malformation (CTM) #

Zalepugas D et al. · Computational and structural biotechnology journal · 2025

Thoracic · Comparative study · n: 14 patients

No difference reported
“While time demands remain a limitation, VR as a digital twin aligns with precision medicine and smart hospital paradigms.”

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Comparison of virtual reality and computed tomography in the preoperative planning of complex tibial plateau fractures #

Colcuc C et al. · Archives of orthopaedic and trauma surgery · 2024

Orthopedics · Comparative study · n: 30 cases

Mixed
“The mean planned operative time of 156 (SD 47) minutes was significantly lower (p < 0.001) in the VR group than in the CT group (172 min; SD 44).”

156

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Augmented and virtual reality imaging for collaborative planning of structural cardiovascular interventions: a proof-of-concept and validation study #

Jacquemyn X et al. · Journal of medical imaging (Bellingham, Wash.) · 2024

Adult cardiac & structural heart · Validation study · n: 5 patients

Descriptive
“The time to complete the entire task was 892 ± 407 s on average, with VR measurements being faster than AR ( 804 ± 483 versus 957 ± 257 s , P = 0.045 ).”

P = 0.045

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Unifocalization of Major Aortopulmonary Collateral Arteries (MAPCAs) and Native Pulmonary Arteries in Infancy-Application of 3D Printing and Virtual Reality #

Kolcz J et al. · Journal of cardiovascular development and disease · 2024

Congenital heart · Prospective cohort · n: 9 patients

Positive finding
“The intervention group had shorter operative and cardiopulmonary bypass times compared to the control group.”

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Early Experience of Surgical Planning for STA-MCA Bypass Using Virtual Reality #

Kim NC et al. · World neurosurgery · 2023

Neurosurgery · Comparative study · n: 30 patients (17 VR, 13 control)

No significant difference
“No significant difference were found in the procedure time or craniotomy size between the 2 groups.”

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Show the other 65 studies

Virtual Resection Specimen Interaction Using Augmented Reality Holograms to Guide Margin Communication and Flap Sizing #

Necker FN et al. · Otolaryngology--head and neck surgery · 2023

ENT / head & neck · Cadaveric study

Descriptive
“During an operative workshop, a surgeon using AR glasses projected virtual, annotated specimen models back into the resection bed onto a cadaver within approximately 10 minutes.”

10 minutes

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Neuro-oncological augmented reality planning for intracranial tumor resection #

Van Gestel F et al. · Frontiers in neurology · 2023

Neurosurgery · Prospective cohort · n: 20 patients

Positive finding
“The overall planning time (AR = 119 ± 44 s, conventional = 187 ± 56 s) was significantly reduced through the adoption of the AR workflow”

AR = 119 ± 44 s, conventional = 187 ± 56 s

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Fast-track virtual reality software to facilitate 3-dimensional reconstruction in congenital heart disease #

Bertelli F et al. · Interdisciplinary cardiovascular and thoracic surgery · 2023

Congenital heart · Validation study · n: 5 patients

Positive finding
“All our participants recreated 3D models in a relatively short time, maintaining a good overall quality (average quality score ≥ 3 on a scale of 1-5).”

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Mixed Reality for Cranial Neurosurgical Planning: A Single-Center Applicability Study With the First 107 Subsequent Holograms #

Colombo E et al. · Operative neurosurgery (Hagerstown, Md.) · 2023

Neurosurgery · Prospective cohort · n: 107 cases

Descriptive
“Mean hologram segmentation time was 39.4 ± 20.4 minutes.”

39.4 ± 20.4 minutes

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Percutaneous Kidney Puncture with Three-dimensional Mixed-reality Hologram Guidance: From Preoperative Planning to Intraoperative Navigation #

Porpiglia F et al. · European urology · 2022

Urology · Comparative study · n: 10 patients

Mixed
“Matched pair analysis with the standard ECIRS group revealed a significantly shorter radiation exposure time for the 3D MR group (p < 0.001) even though the puncture time was longer in comparison to the standard group (p < 0.001).”

p < 0.001

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A Novel 3D Visualized Operative Procedure in the Single-Stage Complete Repair With Unifocalization of Pulmonary Atresia With Ventricular Septal Defect and Major Aortopulmonary Collateral Arteries #

Qiu H et al. · Frontiers in cardiovascular medicine · 2022

Congenital heart · Comparative study · n: 20 patients (9 3D-visualised vs 11 conventional)

Mixed
“the median pre-CPB time per MAPCAs was significantly shorter [25.7 (14.0, 46.3) vs. 65 (41.3, 75.0) min, p = 0.031]”

p = 0.031

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Cinematic Rendering in Mixed-Reality Holograms: A New 3D Preoperative Planning Tool in Pediatric Heart Surgery #

Gehrsitz P et al. · Frontiers in cardiovascular medicine · 2021

Congenital heart · Comparative study · n: 26 patients

Positive finding
“3D imaging reduced the intraoperative preparation time (n = 24, 59 ± 23 min vs. 73 ± 43 min, P < 0.05).”

59 ± 23 min vs. 73 ± 43 min

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Virtual Reality in Preoperative Planning of Adolescent Idiopathic Scoliosis Surgery Using Google Cardboard #

De Salvatore S et al. · Neurospine · 2021

Spine · Comparative study · n: 60 patients

Positive finding
“The use of VR led to a significant decrease in operative time and bleeding while increasing the surgeon's satisfaction compared to the control group.”

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Virtual reality and 3D printing improve preoperative visualization of 3D liver reconstructions-results from a preclinical comparison of presentation modalities and user's preference #

Huettl F et al. · Annals of translational medicine · 2021

Hepatobiliary & pancreatic (HPB) · Comparative study · n: 20 cases

Descriptive
“Tumor assignment was significantly shorter with 3D PR models compared to 3D PDF (P<0.001) or VR application (P<0.001).”

P<0.001

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Preoperative evaluation of neurovascular relationships for microvascular decompression: Visualization using Brainvis in patients with idiopathic trigeminal neuralgia #

Wang B et al. · Clinical neurology and neurosurgery · 2021

Neurosurgery · Prospective case series · n: 8 patients

Positive finding
“Moreover, the assessment duration was significantly shorter with the fusion imaging technique than with the three-dimensional MR (P<0.05).”

P<0.05

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Breast Magnetic Resonance Image Analysis for Surgeons Using Virtual Reality: A Comparative Study #

El Beheiry M et al. · JCO clinical cancer informatics · 2021

Plastic & reconstructive · Comparative study

Positive finding
“The MRI analysis time was significantly lower with the DIVA system than with the slice-based visualization for residents, practitioners, and subsequently the entire group (P < .001).”

P < .001

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Use of mixed reality for improved spatial understanding of liver anatomy #

Pelanis E et al. · Minimally invasive therapy & allied technologies · 2020

Hepatobiliary & pancreatic (HPB) · Comparative study

Positive finding
“The median time for correct identification was 23.5 [4-138] s using the magnetic resonance imaging images and 6.00 [1-35] s using HoloLens (p < 0.001)”

p < 0.001

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Three-Dimensional Augmented Reality Visualization Informs Locoregional Therapy in a Translational Model of Hepatocellular Carcinoma #

Park BJ et al. · Journal of vascular and interventional radiology · 2020

Interventional radiology · Comparative study · n: 28 rats

Mixed
“A 37% reduction in fluoroscopy time, from 11.7 min to 7.4 minutes, was observed with AR when compared prospectively, which did not reach statistical significance (P = .12)”

P = .12

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Holographic Reconstructions for Preoperative Planning before Partial Nephrectomy: A Head-to-Head Comparison with Standard CT Scan #

Antonelli A et al. · Urologia internationalis · 2019

Urology · Comparative study · n: 10 patients

Positive finding
“The evaluation time was shorter for HR (mean 1.7 vs. 3.4 min, p < 0.0001).”

p < 0.0001

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The Use of 3-Dimensional, Virtual Reality Models for Surgical Planning of Robotic Partial Nephrectomy #

Shirk JD et al. · Urology · 2019

Urology · Comparative study · n: 60 patients

Positive finding
“When controlling for case complexity and surgeon, patients with 3-dimensional, virtual reality-assisted surgical planning had significantly lower operative time (141 minutes vs 201 minutes, P < .0001), clamp time (13.2 minutes vs 17.4 minutes, P = .0274)”

P < .0001

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Mixed Reality spatial computing for preoperative surgical planning in orthopedic oncology: review of 72 cases and evolution of clinical implementation #

Wong KC et al. · Exploration of Digital Health Technologies · 2026

Orthopedics · Retrospective case series · n: 72 patients

Descriptive
“Since December 2024, generating cinematic-rendered 3D models with the upgraded MR software platform (version 2) has taken an average of 61 minutes (49–156).”

61 minutes

DOI

Visualisation of cardiac magnetic resonance-based anatomic models in virtual reality to evaluate candidacy for transcatheter pulmonary valve replacement in surgically palliated right ventricular outflow tracts #

Wilson HC et al. · Cardiology in the young · 2026

Congenital heart · Retrospective cohort · n: 16 patients · Used Elucis

Descriptive
“Median time for model generation was 20.6 minutes (IQR 18.5, 22.0).”

20.6 minutes

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Technical Feasibility of Virtual Reality-Enhanced Three-Dimensional Rotational Angiography: A Retrospective Analysis of a Novel Imaging Approach for Interventional Procedures in the Pediatric Cardiac Catheterization Laboratory #

Szeliga J et al. · Pediatric cardiology · 2026

Congenital heart · Retrospective case series · n: 62 procedures

Descriptive
“Median VR processing times were 3.0 min for model generation, 5.0 min for refinement, 4.0 min for procedural simulation, and 7.0 min for extended anatomical analysis, defined as immersive evaluation of anatomical structures beyond the primary contrast-opacified target region.”

3.0 min

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Mixed Reality-Assisted Thoracic Endovascular Aortic Repair: A Retrospective Study on Efficacy and Safety #

Gu JJ et al. · Annals of noninvasive electrocardiology · 2026

Vascular · Retrospective cohort · n: 46 patients

Positive finding
“Compared with the control group, the MR group exhibited significantly shorter operation duration (70.91 ± 8.533 vs. 77.48 ± 8.474 min, Z = -2.785, p = 0.005)”

p = 0.005

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B-onic Platform: A Single-Center Clinical Evaluation of an Integrated FabLab Workflow for Patient-Specific Surgical Planning and XR-Based Validation #

Cebrián-Carretero JL et al. · Journal of clinical medicine · 2026

Multi-specialty · Retrospective cohort · n: 308 cases

Positive finding
“Mean preoperative planning time was reduced by 34% (-42 h; 95% CI: -48 to -36 h; p < 0.01) compared with historical controls.”

34%

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Exploring the advantages of mixed reality technology in Robot-assisted laparoscopic partial adrenalectomy #

Zou XC et al. · World journal of surgical oncology · 2026

Urology · Retrospective cohort · n: 82 patients

Positive finding
“Postoperative statistics indicated that the operation time for the MR group was significantly shorter than that of the control group (102.00(98.00 103.00) minutes vs. 103.50(101.00 106.75) minutes, p = 0.017).”

p = 0.017

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Thoracoscopic surgery for congenital pulmonary malformations in infants: a preliminary comparative evaluation of virtual reality-guided preoperative planning versus standard imaging #

Pierucci UM et al. · Surgical endoscopy · 2026

Thoracic · Retrospective cohort · n: 50 patients

No significant difference
“Median operative time was 183 versus 248 min (p = 0.42).”

p = 0.42

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An attempt to evaluate the use of mixed reality in surgically treated pediatric oncology patients #

Bronowicki K et al. · NPJ digital medicine · 2025

Multi-specialty · Retrospective cohort · n: 9 patients

No significant difference
“Although a slight increase in procedure time was observed in a few cases, MR did not significantly prolong SP or H.”

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Role of mixed reality in the workflow of complex neurooncological surgeries: a case analysis in thalamic surgery #

Zanuttini L et al. · Acta neurochirurgica · 2025

Neurosurgery · Retrospective case series · n: 9 patients (10 procedures)

Descriptive
“The additional planning time for segmentation averaged 45 min.”

45 min

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Minimally invasive approaches using virtual reality planning in elective aneurysm surgery #

Greuter L et al. · Frontiers in surgery · 2025

Neurosurgery · Retrospective cohort · n: 159 patients

No significant difference
“Operative time was shorter in the VR group but lacked statistical significance”

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Mixed reality in neurosurgery: redefining the paradigm for arteriovenous malformation planning and navigation to improve patient outcomes #

Najera E et al. · Neurosurgical focus · 2024

Neurosurgery · Retrospective case series · n: 10 patients

Descriptive
“The mean surgical duration was approximately 5 hours 11 minutes, with a mean intraoperative blood loss of 507.5 ml.”

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Virtual Reality Planning of Microvascular Decompression in Trigeminal Neuralgia: Technique and Clinical Outcome #

Fabrig OD et al. · Journal of neurological surgery. Part A, Central European neurosurgery · 2024

Neurosurgery · Retrospective case series · n: 26 patients

Descriptive
“The VR planning was well integrated into the clinical workflow, and imaging processing time was 30 to 40 minutes.”

30 to 40 minutes

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The clinical application value of mixed reality in robotic laparoscopic partial nephrectomy #

Zou XC et al. · Frontiers in oncology · 2024

Urology · Retrospective cohort · n: 68 patients

Positive finding
“In comparison to traditional RAPN, MR technology demonstrates the ability to decrease operation time and warm ischemia time all the while maintaining equivalent curative outcomes.”

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Application value of mixed reality in hepatectomy for hepatocellular carcinoma #

Zhu LY et al. · World journal of gastrointestinal surgery · 2022

Hepatobiliary & pancreatic (HPB) · Retrospective cohort · n: 95 patients

Positive finding
“Compared to traditional hepatectomy in Group B, MR-assisted hepatectomy in Group A yielded a shorter operation time (202.86 ± 46.02 min vs 229.52 ± 57.13 min, P = 0.003)”

P = 0.003

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Microsurgical clipping of middle cerebral artery aneurysms: preoperative planning using virtual reality to reduce procedure time #

Steineke TC, Barbery D · Neurosurgical focus · 2021

Neurosurgery · Retrospective cohort · n: 21 patients

Positive finding
“The mean procedure time was significantly lower for the VR group compared with the control group (247.80 minutes vs 328.27 minutes; p = 0.0115), particularly for the patients with a CC score of 2 (95% CI, p = 0.0064).”

p = 0.0115

DOIPubMed

Intraoperative Three-dimensional Virtual Reality and Computed Tomographic Guidance in Temporomandibular Joint Arthroplasty of Syndromic Craniofacial Dysostoses #

Bradley D et al. · Plastic and reconstructive surgery. Global open · 2019

Oral & maxillofacial / craniofacial · Retrospective case series · n: 4 patients

Positive finding
“The average operative time in the traditional CT guidance group was 300 minute versus 134 minutes in the 3D VR group.”

134 minutes

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Virtual reality digital surgical planning for jaw reconstruction: a usability study #

Manzie T et al. · ANZ journal of surgery · 2023

ENT / head & neck · Survey/user study

Positive finding
“Surgeons were able to perform the steps in an efficient time despite limited experience.”

DOIPubMed

Virtual Reality for Surgical Planning - Evaluation Based on Two Liver Tumor Resections #

Reinschluessel AV et al. · Frontiers in surgery · 2022

Hepatobiliary & pancreatic (HPB) · Qualitative/user study · n: 2 patients

Descriptive
“The participants used on average 14.3 min (SD = 3.59) to plan the cases in VR.”

14.3 min

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Virtual Reality Cardiac Surgical Planning Software (CorFix) for Designing Patient-Specific Vascular Grafts: Development and Pilot Usability Study #

Kim B et al. · JMIR cardio · 2022

Congenital heart · Survey/user study · n: 1 patient dataset

Descriptive
“The average times for creating 1 bifurcated and 1 tube-shaped graft after a single 10-minute training session were 13.40 and 5.49 minutes, respectively, with 3 out 5 bifurcated and 1 out of 5 tube-shaped graft designs being in the benchmark range of hepatic flow distribution.”

13.40 and 5.49 minutes

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Evaluation of how users interface with holographic augmented reality surgical scenes: Interactive planning MR‐Guided prostate biopsies #

Velazco-Garcia JD et al. · The International Journal of Medical Robotics and Computer Assisted Surgery · 2021

Urology · Survey/user study

Descriptive
“The studies indicated that using a joystick improved the interactive capacity and enabled operator to plan MRgPBx in less time.”

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Extended reality for perforator visualization in deep inferior epigastric perforator autologous breast reconstruction: A systematic review #

Zijlstra K et al. · JPRAS open · 2026

Plastic & reconstructive · Systematic review

Positive finding
“XR use decreased operative time, with AR reducing intraoperative perforator localization time from 20 min using handheld Doppler US to 2.3 min.”

2.3 min

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Mixed reality applications in percutaneous stone surgery: A systematic review and meta-analysis of stone-free rate and perioperative complications #

Lo CY et al. · BJUI compass · 2026

Urology · Systematic review

No significant difference
“There was no statistically significant difference in puncture time between MR-assisted and standard groups (SMD = -0.64; 95% CI -2.22 to 0.93; p = 0.42), with considerable heterogeneity.”

p = 0.42

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Revolutionizing Head and Neck Reconstruction: The Integration of Artificial Intelligence and Virtual Reality in Surgical Practice #

Ghasemi S et al. · Preprints.org · 2025

ENT / head & neck · Preprint (narrative review)

Positive finding
“AI algorithms increased the accuracy of tumor detection and treatment planning, while VR-based planning and augmented reality guidance improved surgical margins and reduced operative time.”

DOI

Extended reality for mapping perforator-based flaps in breast reconstruction: a systematic review and meta-analysis #

Lacey H et al. · JPRAS open · 2025

Plastic & reconstructive · Systematic review

Positive finding
“Preoperative VR was associated with shorter operative times than conventional Doppler ultrasound (478±56.94 vs 606.29 ± 81.94 min, P<0.05).”

P<0.05

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The use of extended reality in microsurgical free flap planning - A systematic review #

Rasmussen KH et al. · JPRAS open · 2025

Plastic & reconstructive · Systematic review

Positive finding
“Virtual reality demonstrated better visualization of patient-specific anatomy and was more time efficient than CT angiography.”

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Use of Virtual Reality and 3D Models in Contemporary Practice of Cardiology #

Minga I et al. · Current cardiology reports · 2024

Adult cardiac & structural heart · Narrative review

Positive finding
“The implementation of virtual reality has been shown to yield cost savings in healthcare, reduce procedure time, minimize radiation exposure, lower intravenous contrast usage, and decrease the extent of anesthesia required.”

DOIPubMed

Advanced outcomes of mixed reality usage in orthognathic surgery: a systematic review #

Stevanie C et al. · Maxillofacial plastic and reconstructive surgery · 2024

Oral & maxillofacial / craniofacial · Systematic review

Positive finding
“MR technology significantly improves OGS planning efficiency by providing pre-surgical information and serving as an intraoperative navigation tool, reducing surgical time without compromising outcomes.”

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Three-dimensional technologies in presurgical planning of bone surgeries: current evidence and future perspectives #

Portnoy Y et al. · International journal of surgery (London, England) · 2023

Orthopedics · Narrative review

Positive finding
“Overall, 3D technologies are gradually becoming an integral part of a surgeon's preoperative toolbox, allowing for increased surgical accuracy and reduction of operation time, mainly in complex and unique surgical cases.”

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Optimizing Surgical Performance Using Preoperative Virtual Reality Planning: A Systematic Review #

Laskay NMB et al. · World journal of surgery · 2023

Multi-specialty · Systematic review

Positive finding
“This review demonstrates that time spent rehearsing and visualizing patient-specific anatomical relationships in VR may improve operative efficiency and communication across multiple surgical specialties.”

DOIPubMed

Virtual and augmented reality for preoperative planning in plastic surgical procedures: A systematic review #

Vles MD et al. · Journal of plastic, reconstructive & aesthetic surgery · 2020

Plastic & reconstructive · Systematic review

Positive finding
“Harvesting time (p < 0.012) and operative time (p < 0.01) in DIEP-flap procedures and mandibular angle osteotomies, respectively, were significantly reduced if AR was used.”

p < 0.012

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Patient-Specific 3D-Printed Models and Mixed-Reality Head-Mounted Display Visualization for Aneurysm Clip Ligation Planning: A Methodological Workflow Study #

Haegler J et al. · Brain sciences · 2026

Neurosurgery · Case series · n: 29 patients

Descriptive
“The mean total preparation time (mean ± standard deviation, SD) was 40.6 ± 10.3 min for MR-HMD visualization and 108.8 ± 17.8 min for 3D-printed models, excluding printing, washing, and curing time.”

40.6 ± 10.3 min

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Application of Mixed Reality Technology in the Planning of PCNL for Special Types of Complex Upper Urinary Stones: A Pilot Study #

Liu Y et al. · Urology · 2025

Urology · Feasibility study · n: 15 patients

Descriptive
“The average time for establishing the main tract was 2.3 ± 0.3 minutes, and the average total operative time was 61.5 ± 12.2 minutes.”

2.3 ± 0.3 minutes

DOIPubMed

PreVISE: an efficient virtual reality system for SEEG surgical planning #

Spiegler P et al. · Virtual reality · 2025

Neurosurgery · Technical development

Positive finding
“The system reduces the surgical planning time by 91%.”

91%

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Virtual Reality Planning for Mandible Reconstruction: A Case Report #

Banerjee AR et al. · Plastic and reconstructive surgery. Global open · 2025

Oral & maxillofacial / craniofacial · Case report · n: 1 patient

Descriptive
“VR planning was completed directly by the surgeon without engineer assistance, with a total planning time of 5 minutes.”

5 minutes

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Feasibility of Mixed Reality-assisted physician-modified endografts #

Hatzl J et al. · Journal of vascular surgery cases and innovative techniques · 2025

Vascular · Technical development (phantom)

Positive finding
“In the comparative analysis, the MxR group showed comparable accuracy to the conventional method but required fewer reattempts (3 vs 10) and less time (6.7 vs 14.6 minutes; P < .01).”

6.7 vs 14.6 minutes

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B-onic Suite: An Integrated Platform for Personalized Medical Devices, Real-Time Surgical Planning, and Enhanced Intraoperative Navigation #

Martín Cubillo C et al. · Studies in health technology and informatics · 2025

Multi-specialty · Technical development

Positive finding
“Deployed in routine clinical workflows at La Paz University Hospital, the platform has demonstrated reduced preoperative planning times and improved surgical accuracy.”

DOIPubMed

AI-Enhanced 3D Models in Global Virtual Reality Case Conferences for Surgical Care in a Low-Income Country: Exploratory Study #

Obst M et al. · JMIR formative research · 2025

Plastic & reconstructive · Feasibility study · n: 15 patients

Positive finding
“The process was time-efficient, with a total of under 8 minutes per case for data acquisition and model creation, and resource-efficient with surgeons reporting sufficient quality of smartphone-derived models.”

8 minutes

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Augmented reality and 3D modeling for preoperative planning in microsurgical resection of brain arteriovenous malformations: A proof-of-concept study #

Konovalov A et al. · Surgical neurology international · 2025

Neurosurgery · Case series · n: 20 patients

Descriptive
“Preoperative modeling required 15.3 ± 5.1 min, while AR navigation averaged 12.7 ± 3.2 min.”

15.3 ± 5.1 min

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The Inaugural "Century" of Mixed Reality in Cranial Surgery: Virtual Reality Rehearsal/Augmented Reality Guidance and Its Learning Curve in the First 100-Case, Single-Surgeon Series #

Jean WC et al. · Operative neurosurgery (Hagerstown, Md.) · 2024

Neurosurgery · Case series · n: 100 cases

No significant difference
“Comparing the 17 pairs of matched MxR and non-MxR cases, no statistically significant differences exist in the groups regarding blood loss, length of stay nor duration of surgery.”

DOIPubMed

Virtual Reality Planning in Reconstructive Surgery for Orbital Prosthetic Rehabilitation Using ImmersiveTouch Platform: Preliminary Report #

Arias-Amezquita E et al. · The Journal of craniofacial surgery · 2024

Oral & maxillofacial / craniofacial · Case series · n: 2 patients

Descriptive
“It takes, on average, 10 minutes to place 4 implants in the virtual reality space.”

10 minutes

DOIPubMed

Feasibility of Augmented Reality for Pediatric Giant Supratentorial Tumors: A Report of Three Cases #

Wu Y et al. · Cureus · 2024

Neurosurgery · Case series · n: 3 patients

No difference reported
“However, we observe that substantial time is required to set up the AR system prior to each clinical case discussion by the neurosurgical team.”

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BREAST+: An augmented reality interface that speeds up perforator marking for DIEAP flap reconstruction surgery #

Timóteo R et al. · Healthcare technology letters · 2024

Plastic & reconstructive · Technical development

Positive finding
“The average time taken to mark each perforator is 7.7 ± 6.5 s, with an average absolute error of 6.8 ± 2.6 mm and an estimated average deviation of 3.6 ± 1.4 mm.”

7.7 ± 6.5 s

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Workflow assessment of an augmented reality application for planning of perforator flaps in plastic reconstructive surgery: Game or game changer? #

Berger MF et al. · Digital health · 2023

Plastic & reconstructive · Feasibility study

Descriptive
“The presented setup involved human interaction (no automation, no application programming interface used for data exchange among collaborators) in four different locations with a net workload of 173 min until clinical readiness on the AR system, and the evaluation considers therefore a pre-automation/implementation scenario.”

173 min

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Feasibility study of a mixed reality tool for real 3D visualization and planning of left atrial appendage occlusion #

Pasquali M et al. · Journal of cardiovascular computed tomography · 2022

Adult cardiac & structural heart · Research letter · n: 4 patients

Descriptive
“The morphological analysis of the holographic anatomical models was successfully applied for all the patients (n ​= ​4) independently from the morphology and it was performed in less than 10 minutes.”

less than 10 minutes

DOIPubMed

Single-stage cranioplasty with customized polyetheretherketone implant after tumor resection using virtual reality and augmented reality for precise implant customization and placement: illustrative case #

Rios-Vicil CI et al. · Journal of neurosurgery. Case lessons · 2022

Neurosurgery · Case report · n: 1 patient

Descriptive
“Excellent cosmetic results, decreased operative time, and a feasible workflow were achieved.”

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Same-day Virtual Reality Surgical Planning and Intraoperative Navigation: A New Surgical Workflow for Craniofacial Trauma and Reconstruction #

Mathis S et al. · Plastic and reconstructive surgery. Global open · 2021

Oral & maxillofacial / craniofacial · Conference abstract

Descriptive
“Data import, segmentation, and reduction of fractures within VR took on average approximately 5 minutes, and transfer of the plan to the navigation platform took 4 minutes.”

5 minutes

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Mixed Reality and 3D Printed Models for Planning and Execution of Face Transplantation #

Cho KH et al. · Annals of surgery · 2021

Oral & maxillofacial / craniofacial · Case report · n: 1 patient

Positive finding
“Holographic models required less time and cost for fabrication.”

DOIPubMed

Fast-track virtual reality for cardiac imaging in congenital heart disease #

Raimondi F et al. · Journal of cardiac surgery · 2021

Congenital heart · Technical development (case series) · n: 3 patients

Descriptive
“The median post-processing time to get VR models using DIVA was 5 min in comparison to 8 h (range 8-12 h including printing time) for 3D models (PDF/printed).”

5 min

DOIPubMed

Expanded Endoscopic Endonasal Transtuberculum Approach for Tuberculum Sellae Meningioma: Operative Video With 360-Degree Fly-Through and Surgical Rehearsal in Virtual Reality: 2-Dimensional Operative Video #

Jean WC, Singh A · Operative neurosurgery (Hagerstown, Md.) · 2020

Neurosurgery · Case report (video) · n: 1 patient

Positive finding
“The three-dimensional renderings are quick to set up (15 min), and the examination of the anatomy is useful for choosing the surgical approach.”

15 min

DOIPubMed

Augmented reality mastectomy surgical planning prototype using the HoloLens template for healthcare technology letters #

Amini S, Kersten-Oertel M · Healthcare technology letters · 2019

Plastic & reconstructive · Technical development

Descriptive
“This method can be quicker than the traditional way and eliminates sizer implants from the process.”

DOIPubMedFree full text

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Summarises published research on VR/AR surgical planning across all platforms. Not product labelling. For Elucis indications see /elucis.

Intended for healthcare professionals.

Summaries and quotes describe each study's methods and the findings its authors report. They are not claims by Realize Medical and may contain errors: please read the original paper. Inclusion is not an endorsement of any product or use.