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Research Library · Independent literature review

Multi-specialty: VR and AR surgical planning research

The library holds 47 Multi-specialty studies, published 2017–2026; 24 of them since 2024.

Study designs: 2 comparative or prospective studies, 2 retrospective studies, 7 surveys and user studies, 17 reviews and 19 case reports, case series and technical reports.

Multi-specialty: studies by questionBar chart. Multi-specialty: studies by question. Department adoption 15, Prefer 3D planning 7, Anatomy understanding 6, Changes the plan 5, Accuracy 5, Time 4.RESEARCH LIBRARY · INDEPENDENT LITERATURE REVIEWMulti-specialty: studies by question47 studies in the libraryDepartment adoption15Prefer 3D planning7Anatomy understanding6Changes the plan5Accuracy5Time4Positive findingMixedDescriptiveNo significant differenceRealize Medical Research Library · 631 studies · updated 2026-10-03

Key findings by question

Quoted from the studies. Each question lists the studies that report on it.

Do surgeons actually want to plan in 3D?

Of 7 studies with a finding on this question: 4 report a positive finding, 1 mixed, 2 descriptive. These reflect what each study's authors report.

  • Positive finding
    “According to experts, the most useful areas are medical education and surgical planning.”

    Veloso 2022 · Survey/user study · n: 22 experts

  • Positive finding
    “A subjective pilot study with 10 clinicians (4 experienced, 6 less experienced; roles: surgeons/trainees), conducted following ITU-R BT.500-15 methodology, reports consistently positive ratings (4.2-4.9/5 on a 5-point Likert scale) on perceived accuracy, responsiveness, and usefulness, indicating potential for clinical and educational scenarios.”

    Trioux 2026 · Technical development · n: 10 clinicians

  • Positive finding
    “Segmentation-based visualization was implemented for preoperative planning in two patients with skull-based malignancies; the surgical team described the 3D workflow as useful for operative planning.”

    Oudeh 2026 · Preprint (experience report)

Does it change the surgical plan?

Of 5 studies with a finding on this question: 3 report a positive finding, 2 mixed. These reflect what each study's authors report.

  • Positive finding
    “While XR technologies improved surgeon confidence and altered surgical strategies in several cases, most studies were small and single-center feasibility evaluations.”

    Afroz 2026 · Systematic review · n: 30 studies

  • Positive finding
    “VR was the most utilized technology (17 studies), improving spatial understanding and prompting plan modifications in 32%-52% of cases (e.g., lung segmentectomies, TAVR).”

    Khubzan 2026 · Systematic review

  • Positive finding
    “Notably, surgical planning using VR led to more frequent changes in surgical plans compared to planning with other visualization methods when surgeons reassessed their initial plans.”

    Queisner 2024 · Systematic review

Multi-specialty studies on this questionAll specialties

Does it improve anatomical understanding?

Of 6 studies with a finding on this question: 6 report a positive finding. These reflect what each study's authors report.

  • Positive finding
    “Ninety-two percent of surveyed surgeons reported improved 3D anatomical understanding and enhanced intraoperative safety.”

    Cebrián-Carretero 2026 · Retrospective cohort · n: 308 cases

  • Positive finding
    “Stereoscopic vision as provided by commercially available VR headset helps resolve ambiguity inherent to virtual scenes containing structures of unknown size and location.”

    Abramson 2025 · Survey/user study

  • Positive finding
    “VRM increased the operating surgeon's confidence 63% of the time.”

    Bramlet 2024 · Survey/user study · n: 12 patients

Does it save time?

Of 4 studies with a finding on this question: 3 report a positive finding, 1 no significant difference. These reflect what each study's authors report.

  • Positive finding
    “Mean preoperative planning time was reduced by 34% (-42 h; 95% CI: -48 to -36 h; p < 0.01) compared with historical controls.”

    Cebrián-Carretero 2026 · Retrospective cohort · n: 308 cases

  • Positive finding
    “This review demonstrates that time spent rehearsing and visualizing patient-specific anatomical relationships in VR may improve operative efficiency and communication across multiple surgical specialties.”

    Laskay 2023 · Systematic review

  • Positive finding
    “Deployed in routine clinical workflows at La Paz University Hospital, the platform has demonstrated reduced preoperative planning times and improved surgical accuracy.”

    Martín Cubillo 2025 · Technical development

All specialties

Is the planning accurate?

Of 5 studies with a finding on this question: 2 report a positive finding, 1 mixed, 2 descriptive. These reflect what each study's authors report.

  • Positive finding
    “Lin's concordance correlation coefficients were 1.00 and 0.98 for the circumference and angle measurements, respectively, indicating almost perfect strength of agreement between ARPPS and PACS.”

    Dallas-Orr 2020 · Validation study

  • Positive finding
    “AR (8 studies) enhanced intraoperative accuracy, reducing pedicle screw placement errors (98% vs. 91.7% control) and procedure times (e.g., 50% faster spinal screw placement).”

    Khubzan 2026 · Systematic review

  • Mixed
    “No statistically significant difference existed between AR and GS measurements (P = .6208).”

    Chang 2020 · Validation study

Will my department actually use it?

Of 15 studies with a finding on this question: 5 report a positive finding, 1 mixed, 9 descriptive. These reflect what each study's authors report.

  • Positive finding
    “Across diverse oncologic contexts and surgical specialties, 3D reconstruction, printing, and AR were successfully integrated into existing perioperative workflows, with each modality selected based on the specific clinical problem at hand.”

    Oudeh 2026 · Preprint (experience report)

  • Positive finding
    “We show that the presented approach can avoid dropped frames at the typical update rate of 90 frames per second of a desktop-based VR system and, therefore, provide a comfortable user experience even in the presence of more than twenty individual volumes.”

    Faludi 2025 · Technical development

  • Positive finding
    “The testing of the algorithm for the application of AR technology in the surgical treatment of primary and recurrent pelvic tumors demonstrated both a technical possibility and reproducibility of this algorithm and the AR technology itself in clinical practice.”

    Ivanov 2023 · Case series · n: 11 patients

Studies (47)

Evaluating the Performance of Augmented Reality in Displaying Magnetic Resonance Imaging-Derived Three-Dimensional Holographic Models #

Chang F et al. · Journal of medical imaging and radiation sciences · 2020

Multi-specialty · Validation study

“No statistically significant difference existed between AR and GS measurements (P = .6208).”

P = .6208

DOIPubMed

Comparing Computed Tomography-Derived Augmented Reality Holograms to a Standard Picture Archiving and Communication Systems Viewer for Presurgical Planning: Feasibility Study #

Dallas-Orr D et al. · JMIR perioperative medicine · 2020

Multi-specialty · Validation study

“Lin's concordance correlation coefficients were 1.00 and 0.98 for the circumference and angle measurements, respectively, indicating almost perfect strength of agreement between ARPPS and PACS.”

1.00 and 0.98

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B-onic Platform: A Single-Center Clinical Evaluation of an Integrated FabLab Workflow for Patient-Specific Surgical Planning and XR-Based Validation #

Cebrián-Carretero JL et al. · Journal of clinical medicine · 2026

Multi-specialty · Retrospective cohort · n: 308 cases

“Mean preoperative planning time was reduced by 34% (-42 h; 95% CI: -48 to -36 h; p < 0.01) compared with historical controls.”

34%

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An attempt to evaluate the use of mixed reality in surgically treated pediatric oncology patients #

Bronowicki K et al. · NPJ digital medicine · 2025

Multi-specialty · Retrospective cohort · n: 9 patients

“Although a slight increase in procedure time was observed in a few cases, MR did not significantly prolong SP or H.”

DOIPubMedFree full text

The importance of stereoscopic vision in virtual surgical planning #

Abramson ZR et al. · International Journal of Radiology & Radiation Therapy · 2025

Multi-specialty · Survey/user study

“Stereoscopic vision as provided by commercially available VR headset helps resolve ambiguity inherent to virtual scenes containing structures of unknown size and location.”

DOI

A usability analysis of augmented reality and haptics for surgical planning #

Kazemipour N et al. · International journal of computer assisted radiology and surgery · 2024

Multi-specialty · Survey/user study

“Both novices and experts preferred the AR system for pedicle screw placement.”

DOIPubMed

Virtual Reality for Preoperative Surgical Planning in Complex Pediatric Oncology #

Bramlet M et al. · Journal of laparoendoscopic & advanced surgical techniques. Part A · 2024

Multi-specialty · Survey/user study · n: 12 patients

“VRM increased the operating surgeon's confidence 63% of the time.”

63%

DOIPubMed

Interaction models for surgical planning in eXtended Reality. Challenges in radiologist-surgeon communication #

Latorre-Rojas et al. et al. · 2023 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops (VRW) · 2023

Multi-specialty · Conference paper (qualitative)

DOI

Mixed Reality in Surgery - a Delphi study #

Veloso R et al. · Kalpa publications in computing · 2022

Multi-specialty · Survey/user study · n: 22 experts

“According to experts, the most useful areas are medical education and surgical planning.”

DOIFree full text

Clinical acceptance of advanced visualization methods: a comparison study of 3D-print, virtual reality glasses, and 3D-display #

Muff JL et al. · 3D printing in medicine · 2022

Multi-specialty · Survey/user study

“Possible change in treatment was reported using 3D-Print in 33%, VR-Glasses in 44%, and 3D-Display in 33% of participants.”

44%

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A comparison of input devices for precise interaction tasks in VR-based surgical planning and training #

Allgaier M et al. · Computers in biology and medicine · 2022

Multi-specialty · Survey/user study

“Although no device stands out for both applications, most participants preferred using the VR Ink, followed by the controller and finally the data gloves and craniotome.”

DOIPubMedFree full text

Immersive extended reality (XR) in oncology: a scoping review of virtual reality (VR) and mixed reality (MR) applications for 3D solid tumor visualization #

Afroz S, Zhang L · Frontiers in Virtual Reality · 2026

Multi-specialty · Systematic review · n: 30 studies

“While XR technologies improved surgeon confidence and altered surgical strategies in several cases, most studies were small and single-center feasibility evaluations.”

DOI

Virtual Reality in Robotic Surgery: Training, Skill Transfer, and Preoperative Planning — A Narrative Review #

Ahmad S · Max Healthcare Medical Journal (Max Healthcare Institute) · 2026

Multi-specialty · Narrative review

DOI

The digital evolution of surgical planning: a systematic review of immersive and interactive technologies #

Khubzan WD et al. · Frontiers in surgery · 2026

Multi-specialty · Systematic review

“VR was the most utilized technology (17 studies), improving spatial understanding and prompting plan modifications in 32%-52% of cases (e.g., lung segmentectomies, TAVR).”

32%-52%

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A review of head-mounted devices for surgical education, preoperative planning and intraoperative navigation #

Singh R et al. · Updates in surgery · 2026

Multi-specialty · Systematic review

“Typical limitations were small participant sizes, non-standardized outcome measures, and a lack of unified assessment frameworks.”

DOIPubMed

Advancing Surgical Practice With Mixed Reality: Current Innovations and Future Prospects #

Ke Y, Hu K · MedComm – Future Medicine · 2025

Multi-specialty · Narrative review

“However, current limitations include insufficient computational and display capabilities of head‐mounted displays, inadequate accuracy in spatial registration, high costs, workflow complexity, and unresolved ethical concerns.”

DOI

A Comprehensive Review of Food and Drug Administration (FDA)-Cleared Virtual Reality Technologies in Radiology #

Avakian A · Cureus · 2025

Multi-specialty · Narrative review

DOIPubMedFree full text

Digital imaging, virtual and augmented reality #

Noguera Aguilar JF · Cirugia espanola · 2024

Multi-specialty · Narrative review

DOIPubMed

Surgical planning in virtual reality: a systematic review #

Queisner M, Eisenträger K · Journal of medical imaging (Bellingham, Wash.) · 2024

Multi-specialty · Systematic review

“Notably, surgical planning using VR led to more frequent changes in surgical plans compared to planning with other visualization methods when surgeons reassessed their initial plans.”

DOIPubMedFree full text

Role of eXtended Reality use in medical imaging interpretation for pre-surgical planning and intraoperative augmentation #

Kantor T et al. · Journal of medical imaging (Bellingham, Wash.) · 2024

Multi-specialty · Narrative review

“However, adoption faces challenges such as high costs, infrastructure needs, and regulatory hurdles.”

DOIPubMedFree full text

Show the other 27 studies

Head Mounted Displays in Surgical Training and Planning: A Literature Review #

Ferrier-Barbut É et al. · Interaction Homme-Machine · 2023

Multi-specialty · Systematic review · n: 12 studies

“Regarding training, even if there is evidence demonstrating learning benefits, these do not seem to transpose to real environments.”

DOI

Development of Holoeyes Holographic Image-Guided Surgery and Telemedicine System: Clinical Benefits of Extended Reality (Virtual Reality, Augmented Reality, Mixed Reality), The Metaverse, and Artificial Intelligence in Surgery with a Systematic Review #

Sugimoto M, Sueyoshi T · Medical Research Archives · 2023

Multi-specialty · Narrative review

DOIFree full text

Immersive Virtual Reality for Patient-Specific Preoperative Planning: A Systematic Review #

Lan L et al. · Surgical innovation · 2023

Multi-specialty · Systematic review

“Preoperative iVR did not significantly improve patient-specific outcomes of operative time, blood loss, complications, and length of stay, but may decrease fluoroscopy time.”

DOIPubMedFree full text

Mixed Reality in Modern Surgical and Interventional Practice: Narrative Review of the Literature #

Vervoorn MT et al. · JMIR serious games · 2023

Multi-specialty · Narrative review

“Limitations primarily seem to be related to constraints associated with head-mounted display.”

DOIPubMedFree full text

Optimizing Surgical Performance Using Preoperative Virtual Reality Planning: A Systematic Review #

Laskay NMB et al. · World journal of surgery · 2023

Multi-specialty · Systematic review

“This review demonstrates that time spent rehearsing and visualizing patient-specific anatomical relationships in VR may improve operative efficiency and communication across multiple surgical specialties.”

DOIPubMed

On the Use of Virtual Reality for Medical Imaging Visualization #

Pires F et al. · Journal of digital imaging · 2021

Multi-specialty · Narrative review

“Our results suggest that prerequisites such as real-time performance and minimum latency pose the greatest limitations for clinical adoption and need to be addressed.”

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[Extended reality technologies for support of surgical workflows] #

Rüger C et al. · Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020

Multi-specialty · Narrative review

“In preoperative planning XR can also offer advantages, although technical limitations often impede routine use; however, for cases of intraoperative use informative evaluation studies are mostly lacking, so that an assessment is not yet possible in a meaningful way.”

DOIPubMed

Application of Mixed Reality Technology in Visualization of Medical Operations #

Gao Y et al. · Chinese medical sciences journal · 2019

Multi-specialty · Narrative review

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Surgilink-Mr: Bounded Planar Cutting and Bidirectional CT-Mesh Interaction for Surgical Mixed Reality Planning and Training #

Trioux A et al. · Image, Video, and Multidimensional Signal Processing Workshop · 2026

Multi-specialty · Technical development · n: 10 clinicians

“A subjective pilot study with 10 clinicians (4 experienced, 6 less experienced; roles: surgeons/trainees), conducted following ITU-R BT.500-15 methodology, reports consistently positive ratings (4.2-4.9/5 on a 5-point Likert scale) on perceived accuracy, responsiveness, and usefulness, indicating potential for clinical and educational scenarios.”

4.2-4.9/5

DOI

Three-Dimensional Imaging, Printing, and Mixed Reality in Surgical Oncology: A Feasibility and Implementation Framework at a Comprehensive Cancer Center #

Oudeh A et al. · Preprints.org · 2026

Multi-specialty · Preprint (experience report)

“Segmentation-based visualization was implemented for preoperative planning in two patients with skull-based malignancies; the surgical team described the 3D workflow as useful for operative planning.”

DOI

Consistent Perspective Alignment in Multiuser Mixed Reality for Collaborative Surgical Pre-Planning #

Menon MM et al. · 2025 IEEE 6th India Council International Subsections Conference (INDISCON) · 2025

Multi-specialty · Technical development

DOI

Mixed Reality as a tool for enhancing precision in surgery planning #

Gomez de Cadiz A et al. · AHFE international · 2025

Multi-specialty · Conference paper

DOI

Multi-volume rendering using depth buffers for surgical planning in virtual reality #

Faludi B et al. · International journal of computer assisted radiology and surgery · 2025

Multi-specialty · Technical development

“We show that the presented approach can avoid dropped frames at the typical update rate of 90 frames per second of a desktop-based VR system and, therefore, provide a comfortable user experience even in the presence of more than twenty individual volumes.”

DOIPubMedFree full text

Virtual reality-augmented differentiable simulations for digital twin applications in surgical planning #

Cremese R et al. · Scientific reports · 2025

Multi-specialty · Technical development

DOIPubMedFree full text

B-onic Suite: An Integrated Platform for Personalized Medical Devices, Real-Time Surgical Planning, and Enhanced Intraoperative Navigation #

Martín Cubillo C et al. · Studies in health technology and informatics · 2025

Multi-specialty · Technical development

“Deployed in routine clinical workflows at La Paz University Hospital, the platform has demonstrated reduced preoperative planning times and improved surgical accuracy.”

DOIPubMed

Extended Reality in Medical Diagnosis and Surgical Planning #

Raisamo R et al. · Studies in health technology and informatics · 2025

Multi-specialty · Experience report

“The results demonstrate that XR technologies can improve medical data understanding, for example, by providing efficient interaction techniques and clear visualizations.”

DOIPubMed

An innovative mixed reality approach for Robotics Surgery #

Rus G et al. · IOP Conference Series Materials Science and Engineering · 2024

Multi-specialty · Technical development

DOI

SurgiColab: Collaborative Mixed Reality for Enhanced Pre-Surgical Planning with 3D Anatomical Models #

Prabhakaran S et al. · International Conference on Biomedical Engineering · 2024

Multi-specialty · Technical development

DOI

Experience in the Application of Augmented Reality Technology in the Surgical Treatment of Patients Suffering Primary and Recurrent Pelvic Tumors #

Ivanov VM et al. · Journal of personalized medicine · 2023

Multi-specialty · Case series · n: 11 patients

“The testing of the algorithm for the application of AR technology in the surgical treatment of primary and recurrent pelvic tumors demonstrated both a technical possibility and reproducibility of this algorithm and the AR technology itself in clinical practice.”

DOIPubMedFree full text

A DirectX-Based DICOM Viewer for Multi-User Surgical Planning in Augmented Reality #

Zhang M et al. · arXiv (Cornell University) · 2022

Multi-specialty · Preprint (technical development)

DOIFree full text

Virtual reality: a useful simulation tool for planning and training #

Sharma D, Subramaniam KG · Indian journal of thoracic and cardiovascular surgery · 2022

Multi-specialty · Letter (no abstract)

DOIPubMedFree full text

Application of Mixed Reality in Medical Training and Surgical Planning Focused on Minimally Invasive Surgery #

Sánchez-Margallo JA et al. · Frontiers in Virtual Reality · 2021

Multi-specialty · Technical development · n: 1 patient (plus experimental model)

“The solution developed for medical training was considered a useful tool for training in urological anatomy, facilitating the translation of this knowledge to clinical practice.”

DOI

SlicerVR for Medical Intervention Training and Planning in Immersive Virtual Reality #

Pinter C et al. · IEEE transactions on medical robotics and bionics · 2020

Multi-specialty · Technical development

“SlicerVR is freely available under BSD type license as an extension to 3D Slicer and it has been downloaded over 7,800 times at the time of writing this article.”

7,800

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Use of mixed reality for surgery planning: Assessment and development workflow #

Kumar RP et al. · Journal of biomedical informatics · 2020

Multi-specialty · Technical development

“Furthermore, our clinical use-cases demonstrate that the surgeons perceived the HoloLens to be useful, recommendable to other surgeons and also provided a definitive answer at a multi-disciplinary team meeting.”

DOIPubMedFree full text

Exploring the Benefits of Holographic Mixed Reality for Preoperative Planning with 3D Medical Images #

Mast M et al. · Gesellschaft für Informatik (GI) · 2019

Multi-specialty · Technical development

DOI

Interactive soft tissue modelling for virtual reality surgery simulation and planning #

El said SA et al. · International Journal of Computer Aided Engineering and Technology · 2017

Multi-specialty · Technical development

DOI

MR-Guided Mixed-Reality For Surgical Planning: Set-Up and Perceptual Accuracy #

Srinivasan S et al. · Proc. Intl. Soc. Mag. Reson. Med. 25 (ISMRM 2017), abstract 5545 · 2017

Multi-specialty · Conference abstract

“The current set-up enables visualization and perception of holograms with a margin tolerance of < 6 mm.”

< 6 mm

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Summarises published research on VR/AR surgical planning across all platforms. Not product labelling. For Elucis indications see /elucis.

Intended for healthcare professionals.

Summaries and quotes describe each study's methods and the findings its authors report. They are not claims by Realize Medical and may contain errors: please read the original paper. Inclusion is not an endorsement of any product or use.